Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Stockholders' Equity (Deficit)

v2.4.0.6
Consolidated Statements of Stockholders' Equity (Deficit) (USD $)
Total
Preferred Stock [Member]
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Balance at Dec. 31, 2009 $ (9,869,852)    $ 80,937 $ 182,747,897 $ (192,698,686)
Balance, shares at Dec. 31, 2009      80,936,711    
Issued restricted stock 660    660      
Issued restricted stock, shares      660,000    
Issued warrants in connection with consulting agreement 279,367       279,367   
Cancelled restricted stock       (5) 5   
Cancelled restricted stock, shares      (4,500)    
Issued stock in payment of interest on convertible debt and dividends on convertible preferred stock 476,667   348 476,319  
Issued stock in payment of interest on convertible debt and dividends on convertible preferred stock (in shares) 347,832   347,832    
Issued stock in connection with stock purchase agreement, net of costs 777,458    661 776,797   
Issued stock in connection with stock purchase agreement, net of costs (in shares)      660,541    
Issued stock upon exercise of stock options, net (63,705)    350 (64,055)   
Issued stock upon exercise of stock options, net, shares 350,156    350,156    
Issued Series B and Series C convertible preferred stock, net of costs 64,636,821 11   64,636,810  
Issued Series B and Series C convertible preferred stock, net of costs (in shares)   11,000      
Issued common stock and warrants in connection with direct offering, net of costs 4,309,951   3,158 4,306,793  
Issued common stock and warrants in connection with direct offering, net of costs (in shares)     3,157,896    
Issued stock to 401(k) plan 40,623    53 40,570   
Issued stock to 401(k) plan, shares 53,499    53,499    
Issued stock upon exercise of warrants, net 316,818    158 316,660   
Issued stock upon exercise of warrants, net, shares      157,778    
Effect of change in terms of warrants 800,878       800,878   
Stock compensation expense 597,672       597,672   
Preferred stock dividends (8,206,745)          (8,206,745)
Net (loss) income (49,964,868)          (49,964,868)
Balance at Dec. 31, 2010 4,131,745 11 86,320 254,915,713 (250,870,299)
Balance, shares at Dec. 31, 2010   11,000 86,319,913    
Issued restricted stock 872    872      
Issued restricted stock, shares      872,000    
Issued warrants in connection with consulting agreement           
Cancelled restricted stock (596)    (686) 90   
Cancelled restricted stock, shares      (686,000)    
Issued stock upon exercise of stock options, net (2,498,223)    1,832 (2,500,055)   
Issued stock upon exercise of stock options, net, shares 1,832,673    1,832,673    
Issued stock to 401(k) plan 61,971    35 61,936   
Issued stock to 401(k) plan, shares 35,233    35,233    
Issued stock upon exercise of warrants, net 8,327,190    4,027 8,323,163   
Issued stock upon exercise of warrants, net, shares      4,026,552    
Effect of change in terms of warrants 1,978,818       1,978,818   
Conversion of Series B preferred stock to common stock    (1) 2,999 (2,998)   
Conversion of Series B preferred stock to common stock, shares   (917) 2,998,590    
Effect of beneficial conversion feature of promissory note 24,888       24,888   
Stock compensation expense 3,592,090       3,592,090   
Preferred stock dividends (100,000)          (100,000)
Net (loss) income 5,612,992          5,612,992
Balance at Dec. 31, 2011 21,131,747 10 95,399 266,393,645 (245,357,307)
Balance, shares at Dec. 31, 2011   10,083 95,398,961    
Issued restricted stock 455    455      
Issued restricted stock, shares      455,000    
Issued warrants in connection with consulting agreement           
Cancelled restricted stock (596)    (601) 5   
Cancelled restricted stock, shares      (600,500)    
Issued stock upon exercise of stock options, net 743,295    1,226 742,069   
Issued stock upon exercise of stock options, net, shares 1,225,270    1,225,271    
Cancelled stock upon repurchase from executives (100,875)    (37) (100,838)   
Cancelled stock upon repurchase from executives, shares      (37,500)    
Issued stock to 401(k) plan 50,272    17 50,255   
Issued stock to 401(k) plan, shares 17,390    17,390    
Issued stock upon exercise of warrants, net 1,978,601    6,020 1,972,581   
Issued stock upon exercise of warrants, net, shares      6,020,000    
Effect of change in terms of warrants 496,671       496,671   
Conversion of Series B preferred stock to common stock    (2) 7,014 (7,012)   
Conversion of Series B preferred stock to common stock, shares   (2,145) 7,014,150    
Conversion of Series C preferred stock to common stock    (1) 3,226 (3,225)   
Conversion of Series C preferred stock to common stock, shares   (1,000) 3,226,000    
Short-swing profit returned to the Company 45,473       45,473   
Issued stock for payment of sublicense fee 1,146,000   300 1,145,700  
Issued stock for payment of sublicense fee , shares 300,000   300,000    
Stock compensation expense 2,304,118       2,304,118   
Preferred stock dividends (43,333)          (43,333)
Net (loss) income (29,157,204)          (29,157,204)
Balance at Dec. 31, 2012 $ (1,405,376) $ 7 $ 113,019 $ 273,039,442 $ (274,557,844)
Balance, shares at Dec. 31, 2012   6,938 113,018,772