Exhibit 11.1 NEOPROBE CORPORATION AND SUBSIDIARIES COMPUTATION OF NET LOSS PER SHARE
Twelve Months Ended December 31, 1999 1998 1997 ------------ ------------ ------------ Loss attributable to common stockholders ($ 7,894,523) ($28,032,752) ($23,246,528) Weighted average number of shares outstanding: Weighted average common shares outstanding beginning of period 22,887,910 22,763,430 22,586,527 Weighted average common shares issued during period 115,551 78,802 148,115 ------------ ------------ ------------ Weighted average number of shares outstanding used in computing basic net loss per share 23,003,461 22,842,232 22,734,642 ============ ============ ============ Weighted average number of shares outstanding used in computing diluted net loss per share 23,003,461 22,842,232 22,734,642 ============ ============ ============ Loss per share attributable to common stockholders: Basic ($ 0.34) ($ 1.23) ($ 1.02) ============ ============ ============ Diluted ($ 0.34) ($ 1.23) ($ 1.02) ============ ============ ============