Exhibit 23.1 CONSENT OF INDEPENDENT ACCOUNTANTS We consent to the incorporation by reference in the Registration Statements of Neoprobe Corporation and Subsidiaries listed below of our report dated February 20, 1998, on our audit of the consolidated statements of operations, stockholders' equity, and cash flows of Neoprobe Corporation and Subsidiaries for the year ended December 31, 1997, which report is included in this Annual Report on the Form 10-K. Form S-3 File No. 33-72700 Form S-3 File No. 33-73622 Form SB-2 File No. 33-86000 Form S-3 File No. 33-93438 Form S-3 File No. 33-93858 Form S-3 File No. 333-15989 Form S-8 File No. 33-70074 Form S-8 File No. 33-81410 Form S-8 File No. 333-05143 PricewaterhouseCoopers LLP Columbus, Ohio March 29, 2000