Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stock-based Compensation - Summary of Stock Option Activity (Details)

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Note 4 - Stock-based Compensation - Summary of Stock Option Activity (Details) - USD ($)
 3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Outstanding at beginning of period (in shares) 238,470  
Outstanding at beginning of period, weighted average exercise price (in dollars per share) $ 17.38  
Granted (in shares) 195,000  
Granted, weighted average exercise price (in dollars per share) $ 1.06  
Exercised (in shares) 0 0
Exercised, weighted average exercise price (in dollars per share)  
Canceled and Forfeited (in shares) (1,500)  
Canceled and Forfeited, weighted average exercise price (in dollars per share) $ 1.06  
Expired (in shares) (500)  
Expired, weighted average exercise price (in dollars per share) $ 30.80  
Outstanding at end of period (in shares) 431,470  
Outstanding at end of period, weighted average exercise price (in dollars per share) $ 10.04  
Outstanding at end of period (Year) 8 years 109 days  
Outstanding at end of period  
Exercisable at end of period (in shares) 112,290  
Exercisable at end of period, weighted average exercise price (in dollars per share) $ 25.54  
Exercisable at end of period (Year) 5 years 255 days  
Exercisable at end of period