Quarterly report pursuant to Section 13 or 15(d)

Note 17 - Supplemental Disclosure for Statements of Cash Flows (Details Textual)

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Note 17 - Supplemental Disclosure for Statements of Cash Flows (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 31, 2017
Mar. 31, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Interest Paid       $ 7,400,000 $ 4,200,000
Reclassification of Funds Invested $ 200,000     $ 200,000  
Stock Issued During Period, Shares, Employee Benefit Plan       105,308  
Issuance of Stock to Defined Contribution Plan for Employer Matching Contribution       $ 53,707
Series NN Warrants [Member] | UCSD [Member]          
Class of Warrant or Right, Number of Securities Called by Warrants or Rights   1,000,000   1,000,000  
Class of Warrant or Right, Grants in Period, Estimated Fair Value   $ 334,000   $ 334,000  
Capital Royalty Group, Term Loan [Member]          
Payments to Collection of Collateral on Claims of Default     $ 778,000   778,000
Payments to Prepayment Premium on Claims of Default     $ 2,100,000   $ 2,100,000