Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Revenue From Contracts With Customers (Details Textual)

v3.10.0.1
Note 4 - Revenue From Contracts With Customers (Details Textual) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2018
Jan. 01, 2018
Dec. 31, 2017
Cumulative Effect of New Accounting Principle in Period of Adoption       $ (700,000)
Revenue from Contract with Customer, Including Assessed Tax $ 22,000 $ 287,000    
Contract with Customer, Asset, Impairment Loss 0 $ 0    
Contract with Customer, Payment Term, Minimum   15 days    
Contract with Customer, Payment Term, Maximum   90 days    
Contract with Customer, Asset, Net, Total 10,000 $ 10,000    
Contract with Customer, Transaction Price of Royalties Using Expected Value Method 0 0    
Capitalized Contract Cost, Net, Total 0 $ 0    
INDIA        
Contract with Customer, Term of Contract   8 years    
CHINA        
Contract with Customer, Term of Contract   10 years    
Long-term Contract with Customer [Member]        
Contract with Customer, Performance Obligation Satisfied in Previous Period $ 0      
Retained Earnings [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption       $ (700,000)
Accounting Standards Update 2014-09 [Member] | Sayre Pharmaceuticals [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     $ 700,000  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     (700,000)  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Sayre Pharmaceuticals [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     (100,000)  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Beijing Sinotau Medical Research Co., Ltd. [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     $ (600,000)