Annual report pursuant to Section 13 and 15(d)

Note 11 - Accounts Payable, Accrued Liabilities and Other (Details Textual)

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Note 11 - Accounts Payable, Accrued Liabilities and Other (Details Textual) - USD ($)
Dec. 31, 2018
Dec. 31, 2017
Executive Bonuses, Director Fees, Deferred Salary, and Scientific Advisory Board Fees [Member] | Accrued Liabilities and Other [Member]    
Due to Related Parties, Current, Total $ 1,600,000 $ 975,000
Former Executive [Member]    
Accounts Payable, Disputed   $ 96,000