Annual report pursuant to Section 13 and 15(d)

Supplemental Disclosure for Statements of Cash Flows (Details)

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Supplemental Disclosure for Statements of Cash Flows (Details) (USD $)
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Supplemental Disclosure for Statements of Cash Flows [Abstract]      
Cash paid during the period for interest $ 647,000 $ 4,000 $ 136,000
Issued stock for payment of sublicense fee , shares 300,000    
Issued stock in payment of interest on convertible debt and dividends on convertible preferred stock (in shares)     347,832
Issued stock to 401(k) plan, shares 17,390 35,233 53,499
Value of inventory transferred to fixed assets   25,000 79,000
Debt instrument, stated interest rate 2.80%   7.00%
Portion of insurance premiums financed 267,000   71,000
Equipment acquired under capital lease agreement 9,000    
Deemed dividend 0 0 8,000,000
Deferred stock offering costs reclassified to APIC     $ 223,000