Schedule of Segment Reporting Information, by Segment [Table Text Block] |
Year Ended December 31, 2019 | | | | | | | | | | | | | Royalty revenue | | $ | 16,665 | | | $ | — | | | $ | — | | | $ | 16,665 | | License revenue | | | 9,953 | | | | — | | | | — | | | | 9,953 | | Grant and other revenue | | | 384,776 | | | | 246,432 | | | | — | | | | 631,208 | | Total revenue | | | 411,394 | | | | 246,432 | | | | — | | | | 657,826 | | Cost of revenue | | | 6,667 | | | | — | | | | — | | | | 6,667 | | Research and development expenses, excluding depreciation and amortization | | | 4,795,445 | | | | 542,822 | | | | — | | | | 5,338,267 | | Selling, general and administrative expenses, excluding depreciation and amortization (
1
)
| | | — | | | | 16,990 | | | | 6,113,907 | | | | 6,130,897 | | Depreciation and amortization (
2
)
| | | — | | | | — | | | | 144,512 | | | | 144,512 | | Loss from operations (
3
)
| | | (4,390,718 | ) | | | (313,380 | ) | | | (6,258,419 | ) | | | (10,962,517 | ) | | | | — | | | | — | | | | 17,675 | | | | 17,675 | | Provision for income taxes | | | (284 | ) | | | (20 | ) | | | (403 | ) | | | (707 | ) | Loss from continuing operations | | | (4,391,002 | ) | | | (313,400 | ) | | | (6,241,147 | ) | | | (10,945,549 | ) | Loss from discontinued operations, net of tax effect | | | (2,665 | ) | | | — | | | | — | | | | (2,665 | ) | Net loss | | | (4,393,666 | ) | | | (313,400 | ) | | | (6,241,147 | ) | | | (10,948,214 | ) | Total assets, net of depreciation and amortization: | | | | | | | | | | | | | | | | | United States | | $ | 55,229 | | | $ | 31,449 | | | $ | 4,064,228 | | | $ | 4,150,906 | | International | | | — | | | | — | | | | — | | | | — | | Capital expenditures | | | — | | | | — | | | | 1,258 | | | | 1,258 | |
Year Ended December 31, 2018 | | | | | | | | | | | | | Royalty revenue | | $ | 15,347 | | | $ | — | | | $ | — | | | $ | 15,347 | | License revenue | | | 307,174 | | | | — | | | | — | | | | 307,174 | | Grant and other revenue | | | 494,997 | | | | 351,833 | | | | — | | | | 846,830 | | Total revenue | | | 817,518 | | | | 351,833 | | | | — | | | | 1,169,351 | | Cost of revenue | | | 96,636 | | | | — | | | | — | | | | 96,636 | | Research and development expenses | | | 3,064,115 | | | | 1,157,766 | | | | — | | | | 4,221,881 | | Selling, general and administrative expenses, excluding depreciation and amortization (
1
)
| | | — | | | | 78,606 | | | | 7,469,144 | | | | 7,547,750 | | Depreciation and amortization (
2
)
| | | — | | | | — | | | | 150,385 | | | | 150,385 | | Loss from operations (
3
)
| | | (2,343,233 | ) | | | (884,539 | ) | | | (7,619,529 | ) | | | (10,847,301 | ) | | | | — | | | | — | | | | (5,321,270 | ) | | | (5,321,270 | ) | Benefit from income taxes | | | 1,413 | | | | 534 | | | | 7,806 | | | | 9,753 | | Loss from continuing operations | | | (2,341,820 | ) | | | (884,005 | ) | | | (12,932,993 | ) | | | (16,158,818 | ) | Income from discontinued operations, net of tax effect | | | 1,449 | | | | — | | | | — | | | | 1,449 | | Gain on sale of discontinued operations, net of tax effect | | | 43,053 | | | | — | | | | — | | | | 43,053 | | Net loss | | | (2,297,318 | ) | | | (884,005 | ) | | | (12,932,993 | ) | | | (16,114,316 | ) | Total assets, net of depreciation and amortization: | | | | | | | | | | | | | | | | | United States | | $ | 91,425 | | | | 24,763 | | | | 6,878,129 | | | | 6,994,317 | | International | | | 14,330 | | | | | | | | 381 | | | | 14,711 | | Capital expenditures | | | — | | | | — | | | | 46,192 | | | | 46,192 | |
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