Annual report pursuant to Section 13 and 15(d)

Note 4 - Revenue From Contracts With Customers (Details Textual)

v3.20.1
Note 4 - Revenue From Contracts With Customers (Details Textual) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Jan. 01, 2018
Dec. 31, 2017
Cumulative Effect of New Accounting Principle in Period of Adoption       $ (700,000)
Contract with Customer, Payment Term, Minimum 15 days      
Contract with Customer, Payment Term, Maximum 90 days      
Contract with Customer, Transaction Price of Royalties Using Expected Value Method $ 0      
Revenue from Contract with Customer, Including Assessed Tax 38,000 $ 338,000    
Contract with Customer, Asset, Impairment Loss 0 0    
Capitalized Contract Cost, Net, Total 0      
Contract with Customer, Asset, after Allowance for Credit Loss, Total 0 12,000    
Long-term Contract with Customer [Member]        
Contract with Customer, Performance Obligation Satisfied in Previous Period 0 0    
Grant [Member]        
Revenue Not from Contract with Customer $ 611,000 $ 761,000    
INDIA        
Contract with Customer, Term of Contract 8 years      
CHINA        
Contract with Customer, Term of Contract 10 years      
Retained Earnings [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption       $ (700,000)
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     $ 700,000  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Sayre Pharmaceuticals [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     100,000  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Beijing Sinotau Medical Research Co., Ltd. [Member]        
Cumulative Effect of New Accounting Principle in Period of Adoption     $ 600,000