Note 14 - Segments - Segment Information (Details) - USD ($)
|
3 Months Ended |
6 Months Ended |
|
Jun. 30, 2020 |
Mar. 31, 2020 |
Jun. 30, 2019 |
Mar. 31, 2019 |
Jun. 30, 2020 |
Jun. 30, 2019 |
Dec. 31, 2019 |
Revenue from contract with customer |
|
$ 9,000
|
|
$ 16,000
|
|
$ 24,000
|
$ 30,000
|
|
Grant and other revenue |
|
262,181
|
|
244,199
|
|
403,232
|
282,673
|
|
Revenues, Total |
|
271,101
|
|
260,092
|
|
427,373
|
301,716
|
|
Cost of revenue |
|
357
|
|
238
|
|
966
|
6,364
|
|
Research and development expenses |
|
1,281,779
|
|
1,070,642
|
|
2,281,048
|
1,811,225
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
[1] |
1,310,335
|
|
1,824,874
|
|
3,121,246
|
3,516,611
|
|
Depreciation, Depletion and Amortization, Nonproduction, Total |
[2] |
19,256
|
|
36,726
|
|
36,099
|
73,505
|
|
Loss from operations (3) |
[3] |
(2,340,626)
|
|
(2,672,388)
|
|
(5,011,986)
|
(5,105,989)
|
|
Other income (4) |
[4] |
15,007
|
|
(1,590)
|
|
12,759
|
7,122
|
|
Net loss |
|
(2,325,619)
|
$ (2,673,608)
|
(2,673,178)
|
$ (2,429,061)
|
(4,999,227)
|
(5,102,240)
|
|
Total assets, net of depreciation and amortization |
|
7,106,683
|
|
|
|
7,106,683
|
|
$ 4,150,906
|
Capital expenditures |
|
1,947
|
|
|
|
8,406
|
|
|
Revenue from contract with customer |
|
9,000
|
|
16,000
|
|
24,000
|
30,000
|
|
Loss from operations (3) |
[3] |
(2,340,626)
|
|
(2,672,388)
|
|
(5,011,986)
|
(5,105,989)
|
|
Other expense (4) |
[4] |
15,007
|
|
(1,590)
|
|
12,759
|
7,122
|
|
Income tax benefit |
|
|
|
168
|
|
|
(708)
|
|
Net loss from continuing operations |
|
|
|
(2,673,810)
|
|
|
(5,099,575)
|
|
Income from discontinued operations, net of tax |
|
|
|
632
|
|
|
(2,665)
|
|
Total assets, net of depreciation and amortization: |
|
7,106,683
|
|
|
|
7,106,683
|
|
$ 4,150,906
|
UNITED STATES |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
6,606,683
|
|
8,123,881
|
|
6,606,683
|
8,123,881
|
|
Total assets, net of depreciation and amortization: |
|
6,606,683
|
|
8,123,881
|
|
6,606,683
|
8,123,881
|
|
Non-US [Member] |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
|
|
6,514
|
|
|
6,514
|
|
Total assets, net of depreciation and amortization: |
|
|
|
6,514
|
|
|
6,514
|
|
Royalty [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
8,920
|
|
5,940
|
|
24,141
|
9,090
|
|
Revenue from contract with customer |
|
8,920
|
|
5,940
|
|
24,141
|
9,090
|
|
License [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
9,953
|
|
|
9,953
|
|
Revenue from contract with customer |
|
|
|
9,953
|
|
|
9,953
|
|
Diagnostics Segment [Member] |
|
|
|
|
|
|
|
|
Grant and other revenue |
|
215,458
|
|
196,630
|
|
274,374
|
232,621
|
|
Revenues, Total |
|
224,378
|
|
212,523
|
|
298,515
|
251,664
|
|
Cost of revenue |
|
357
|
|
238
|
|
966
|
6,364
|
|
Research and development expenses |
|
1,193,151
|
|
775,462
|
|
2,150,777
|
1,516,045
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
[1] |
|
|
|
|
|
|
|
Depreciation, Depletion and Amortization, Nonproduction, Total |
[2] |
|
|
|
|
|
|
|
Loss from operations (3) |
[3] |
(969,130)
|
|
(563,177)
|
|
(1,853,228)
|
(1,270,745)
|
|
Other income (4) |
[4] |
|
|
|
|
|
|
|
Net loss |
|
(969,130)
|
|
(562,510)
|
|
(1,853,228)
|
(1,273,587)
|
|
Capital expenditures |
|
|
|
|
|
|
|
|
Loss from operations (3) |
[3] |
(969,130)
|
|
(563,177)
|
|
(1,853,228)
|
(1,270,745)
|
|
Other expense (4) |
[4] |
|
|
|
|
|
|
|
Income tax benefit |
|
|
|
35
|
|
|
(177)
|
|
Net loss from continuing operations |
|
|
|
(563,142)
|
|
|
(1,270,922)
|
|
Income from discontinued operations, net of tax |
|
|
|
632
|
|
|
(2,665)
|
|
Diagnostics Segment [Member] | UNITED STATES |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
107,185
|
|
220,334
|
|
107,185
|
220,334
|
|
Total assets, net of depreciation and amortization: |
|
107,185
|
|
220,334
|
|
107,185
|
220,334
|
|
Diagnostics Segment [Member] | Non-US [Member] |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
|
|
6,514
|
|
|
6,514
|
|
Total assets, net of depreciation and amortization: |
|
|
|
6,514
|
|
|
6,514
|
|
Diagnostics Segment [Member] | Royalty [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
8,920
|
|
5,940
|
|
24,141
|
9,090
|
|
Revenue from contract with customer |
|
8,920
|
|
5,940
|
|
24,141
|
9,090
|
|
Diagnostics Segment [Member] | License [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
9,953
|
|
|
9,953
|
|
Revenue from contract with customer |
|
|
|
9,953
|
|
|
9,953
|
|
Therapeutics Segment [Member] |
|
|
|
|
|
|
|
|
Grant and other revenue |
|
46,723
|
|
47,569
|
|
128,858
|
50,052
|
|
Revenues, Total |
|
46,723
|
|
47,569
|
|
128,858
|
50,052
|
|
Cost of revenue |
|
|
|
|
|
|
|
|
Research and development expenses |
|
88,628
|
|
295,180
|
|
130,271
|
295,180
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
[1] |
972
|
|
3,062
|
|
(550)
|
14,776
|
|
Depreciation, Depletion and Amortization, Nonproduction, Total |
[2] |
|
|
|
|
|
|
|
Loss from operations (3) |
[3] |
(42,877)
|
|
(250,673)
|
|
(863)
|
(259,904)
|
|
Other income (4) |
[4] |
|
|
|
|
|
|
|
Net loss |
|
(42,877)
|
|
(250,657)
|
|
(863)
|
(259,940)
|
|
Capital expenditures |
|
|
|
|
|
|
|
|
Loss from operations (3) |
[3] |
(42,877)
|
|
(250,673)
|
|
(863)
|
(259,904)
|
|
Other expense (4) |
[4] |
|
|
|
|
|
|
|
Income tax benefit |
|
|
|
16
|
|
|
(36)
|
|
Net loss from continuing operations |
|
|
|
(250,657)
|
|
|
(259,940)
|
|
Income from discontinued operations, net of tax |
|
|
|
|
|
|
|
|
Therapeutics Segment [Member] | UNITED STATES |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
36,483
|
|
11,235
|
|
36,483
|
11,235
|
|
Total assets, net of depreciation and amortization: |
|
36,483
|
|
11,235
|
|
36,483
|
11,235
|
|
Therapeutics Segment [Member] | Non-US [Member] |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization: |
|
|
|
|
|
|
|
|
Therapeutics Segment [Member] | Royalty [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Therapeutics Segment [Member] | License [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Corporate Segment [Member] |
|
|
|
|
|
|
|
|
Grant and other revenue |
|
|
|
|
|
|
|
|
Revenues, Total |
|
|
|
|
|
|
|
|
Cost of revenue |
|
|
|
|
|
|
|
|
Research and development expenses |
|
|
|
|
|
|
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
[1] |
1,309,363
|
|
1,821,812
|
|
3,121,796
|
3,501,835
|
|
Depreciation, Depletion and Amortization, Nonproduction, Total |
[2] |
19,256
|
|
36,726
|
|
36,099
|
73,505
|
|
Loss from operations (3) |
[3] |
(1,328,619)
|
|
(1,858,538)
|
|
(3,157,895)
|
(3,575,340)
|
|
Other income (4) |
[4] |
15,007
|
|
(1,590)
|
|
12,759
|
7,122
|
|
Net loss |
|
(1,313,612)
|
|
(1,860,011)
|
|
(3,145,136)
|
(3,568,713)
|
|
Capital expenditures |
|
1,947
|
|
|
|
8,406
|
|
|
Loss from operations (3) |
[3] |
(1,328,619)
|
|
(1,858,538)
|
|
(3,157,895)
|
(3,575,340)
|
|
Other expense (4) |
[4] |
15,007
|
|
(1,590)
|
|
12,759
|
7,122
|
|
Income tax benefit |
|
|
|
117
|
|
|
(495)
|
|
Net loss from continuing operations |
|
|
|
(1,860,011)
|
|
|
(3,568,713)
|
|
Income from discontinued operations, net of tax |
|
|
|
|
|
|
|
|
Corporate Segment [Member] | UNITED STATES |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
6,463,015
|
|
7,892,312
|
|
6,463,015
|
7,892,312
|
|
Total assets, net of depreciation and amortization: |
|
6,463,015
|
|
7,892,312
|
|
6,463,015
|
7,892,312
|
|
Corporate Segment [Member] | Non-US [Member] |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization |
|
|
|
|
|
|
|
|
Total assets, net of depreciation and amortization: |
|
|
|
|
|
|
|
|
Corporate Segment [Member] | Royalty [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Corporate Segment [Member] | License [Member] |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
Revenue from contract with customer |
|
|
|
|
|
|
|
|
|
|