Annual report pursuant to Section 13 and 15(d)

Equity (Details)

v2.4.0.8
Equity (Details) (USD $)
 0 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 1 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended
Sep. 24, 2016
Sep. 30, 2013
Apr. 30, 2013
Feb. 28, 2013
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2013
Minimum [Member]
Dec. 31, 2013
Maximum [Member]
Jun. 30, 2013
Five Year Series II Warrants [Member]
Dec. 31, 2013
Five Year Series II Warrants [Member]
Jun. 30, 2013
Five Year Series II Warrants [Member]
Maximum [Member]
Dec. 31, 2013
Three Year Series JJ Warrants [Member]
Sep. 30, 2013
Three Year Series JJ Warrants [Member]
Sep. 30, 2013
Three Year Series JJ Warrants [Member]
Minimum [Member]
Sep. 30, 2013
Three Year Series JJ Warrants [Member]
Maximum [Member]
Dec. 31, 2013
Series BB Warrants [Member]
Dec. 31, 2011
Series Z Warrants [Member]
Dec. 31, 2013
Series W Warrants [Member]
Dec. 31, 2013
Series HH Warrants [Member]
Jun. 30, 2013
Series HH Warrants [Member]
Dec. 31, 2013
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Sep. 30, 2013
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Dec. 31, 2011
Fair Value, Measurements, Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Sep. 30, 2013
Platinum Montaur Life Sciences Llc Credit Facility [Member]
Dec. 31, 2013
Platinum Montaur Life Sciences Llc Credit Facility [Member]
Mar. 31, 2013
Platinum Montaur Life Sciences Llc Credit Facility [Member]
Series X Warrants [Member]
Dec. 31, 2013
Platinum Montaur Life Sciences Llc Credit Facility [Member]
Series X Warrants And Series Aa Warrants [Member]
Jun. 30, 2013
Platinum Montaur Life Sciences Llc Credit Facility [Member]
Series X Warrants And Series Aa Warrants [Member]
Jun. 30, 2013
General Electric Capital Corporation [Member]
Series HH Warrants [Member]
Jun. 25, 2013
General Electric Capital Corporation [Member]
Series HH Warrants [Member]
Jun. 30, 2013
Preferred Stock [Member]
Dec. 31, 2013
Preferred Stock [Member]
Jun. 30, 2013
Common Stock [Member]
Dec. 31, 2013
Common Stock [Member]
Class of Stock [Line Items]                                                                      
Issued stock in connection with public offerings, net of costs, shares   10,563,381 2,100,000 1,542,389                                                              
Shares Issued Price Per Share   $ 2.84 $ 2.43 $ 3.10                                                              
Warrants, exercise price         3.39     1.97 3.83   3.04 3.04 3.83 3.83 2.00 3.83 2.00     2.49                   2.49 2.49        
Class of Warrant or Right, Term                   5 years                                                  
Derivative liabilities         $ 7,692,087                                 $ 7,692,087 $ 7,700,000 $ 569,000                      
Warrants, weighted average exercise price         $ 3.39                                                            
Warrants exercised                                   60,000 6,000,000               3,000,000                
Issued stock upon exercise of warrants, net, shares                                     6,000,000               3,000,000                
Proceeds from Warrant Exercises                                     1,920,000               1,380,000                
Warrants outstanding         4,542,764           275,000   3,169,015       300,000     301,205                              
placement agent fees as a percentage of gross proceeds   3.30%                                                                  
Conversion of Series B preferred stock to common stock, shares                                                               2,364.9 2,364.9    
Number of common shares underlying Series B Preferred Stock                                                       7,733,223 7,733,223            
Shares conversion, number of common stock equivalent to each preferred stock                                                                   3,270 3,270
Repayments of Notes Payable         5,982,155 1,285,046 62,411                                   4,781,333 4,800,000                  
Proceeds from issuance of common stock   30,000,000     41,303,750 2,724,189 7,198,373                                                        
Warrants, number of securities called by warrants                   275,000       3,169,015 2,100,000 3,800,000         301,205                   301,205        
Warrants, expiration date Sep. 24, 2016                   Jun. 25, 2018   Sep. 24, 2016       Jul. 07, 2015     Jun. 25, 2023                              
Proceeds From Issuance Of Common Stock Net Of Issuance Costs   28,800,000 4,800,000 4,500,000                                                              
PlacementAgentFees   $ 999,000                                                                  
Common stock reserved for future issuance         34,146,916