Annual report pursuant to Section 13 and 15(d)

Agreements (Narrative) (Details)

v3.3.1.900
Agreements (Narrative) (Details) - USD ($)
 1 Months Ended 12 Months Ended
Jul. 31, 2014
Sep. 30, 2013
Aug. 31, 2013
May. 31, 2013
Jul. 31, 2012
Dec. 31, 2011
Nov. 30, 2009
Apr. 30, 2008
Jan. 31, 2002
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Agreements [Line Items]                        
Research and development                   $ 12,777,116    
Reliable Supply Agreement [Member]                        
Agreements [Line Items]                        
Initial term             10 years          
Resolution term             60 days          
Purchases under manufacture and supply agreement                   225,000 $ 300,000 $ 666,000
Purchase orders issued                   1,100,000    
Agreement Expiration             2019-11          
Extended term             3 years          
Nordion Supply Agreement [Member]                        
Agreements [Line Items]                        
Initial term       3 years                
Resolution term       30 days                
Purchases under manufacture and supply agreement                   244,000 505,000 771,000
Purchase orders issued                   150,000    
Agreement Expiration       2016-05                
Notice period       180 days                
PETNET Supply Agreement [Member]                        
Agreements [Line Items]                        
Initial term     3 years                  
Resolution term     30 days                  
Purchases under manufacture and supply agreement                   855,000 2,200,000 1,400,000
Purchase orders issued                   132,000    
Agreement Expiration     2016-08                  
Notice period     60 days                  
Automatic renewal date     1 year                  
OsoBio Supply Agreement [Member]                        
Agreements [Line Items]                        
Resolution term   60 days                    
Purchases under manufacture and supply agreement                   472,000 96,000 1,200,000
Purchase orders issued                   680,000    
Agreement Expiration   2016-12                    
Notice period   12 months                    
Automatic renewal date   2 years                    
Gipharma Supply Agreement [Member]                        
Agreements [Line Items]                        
Initial term   3 years                    
Resolution term   30 days                    
Purchases under manufacture and supply agreement                   677,000 272,000 34,000
Purchase orders issued                   241,000    
Notice period   60 days                    
Automatic renewal date   1 year                    
Notice period to terminate agreement before automatic renew   6 months                    
Lymphoseek License Agreement [Member]                        
Agreements [Line Items]                        
License fee                 $ 25,000      
License maintenance fee                 25,000      
Minimum annual royalty                 $ 25,000      
Research and development                   777,000 353,000 273,000
Lymphoseek Expanded License Agreement [Member]                        
Agreements [Line Items]                        
License fee               $ 25,000        
License maintenance fee               25,000        
Minimum annual royalty               $ 25,000        
Research and development                     25,000 29,000
Tilmanocept License Agreement [Member]                        
Agreements [Line Items]                        
License fee $ 25,000                      
License maintenance fee 25,000                      
Minimum annual royalty $ 25,000                      
Research and development                   152,000 25,000  
Astra Zeneca Agreement [Member]                        
Agreements [Line Items]                        
Research and development                   80,000 81,000 5,000
Astra Zeneca Agreement [Member] | Milestone Payments Based On Achievement Of Certain Clinical Development And Regulatory Filing Milestones [Member]                        
Agreements [Line Items]                        
License fee           $ 5,000,000            
Contingent milestone payment           6,500,000            
Astra Zeneca Agreement [Member] | Milestone Payments Based On Receipt Of Certain Regulatory Approvals And Initiation Of Commercial Sales Of Licensed Product [Member]                        
Agreements [Line Items]                        
Contingent milestone payment           $ 11,000,000            
Alseres Pharmaceuticals Inc [Member]                        
Agreements [Line Items]                        
Research and development                   5,000 $ 42,000 $ 366,000
Contingent milestone payment         $ 2,900,000              
Sublicense execution payment, cash paid         $ 175,000              
Common Stock, shares issued         300,000              
Alseres Pharmaceuticals Inc [Member] | Alseres Milestone Payments Based On Product Registration Or Commercial Sales [Member]                        
Agreements [Line Items]                        
Contingent milestone payment         $ 2,500,000              
Common Stock, shares issuable         950,000              
Alseres Pharmaceuticals Inc [Member] | Milestone Payments Maximum [Member]                        
Agreements [Line Items]                        
Common Stock, shares issuable         1,150,000              
Employment Agreement [Member]                        
Agreements [Line Items]                        
Maximum contingent liability                   $ 2,900,000    
Employment Agreement [Member] | Minimum [Member]                        
Agreements [Line Items]                        
Ratio of entitled salary                   1.20%    
Employment Agreement [Member] | Maximum [Member]                        
Agreements [Line Items]                        
Ratio of entitled salary                   2.00%