Quarterly report pursuant to Section 13 or 15(d)

Note 2 - Liquidity (Details Textual)

v3.10.0.1
Note 2 - Liquidity (Details Textual) - USD ($)
1 Months Ended
Apr. 12, 2018
Apr. 09, 2018
Apr. 02, 2018
Mar. 26, 2018
Jan. 16, 2018
Nov. 02, 2017
Mar. 03, 2017
Dec. 31, 2017
Mar. 31, 2017
CRG [Member]                  
Draws on Letter of Credit   $ 7,100,000              
Sale of Assets to Cardinal Health 414 [Member]                  
Sale of Assets, Cash Received from Buyer as Result of Amendment     $ 6,000,000            
Sale of Assets, Maximum Amount Receivable from Buyer for Unused Portion of Letter of Credit     $ 7,100,000            
PPCO [Member] | Platinum Loan Agreement [Member]                  
Repayments of Debt             $ 7,700,000    
Convertible Debt, Total             1,900,000    
Judicial Ruling [Member] | CRG Loan Agreement, Texas Case [Member]                  
Loss Contingency, Damages Awarded, Value, Additional Amount             7,000,000 $ 7,000,000  
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration               4,100,000  
Judicial Ruling [Member] | CRG Loan Agreement, Texas Case [Member] | Surety Bond [Member]                  
Loss Contingency, Amount Awarded to Other Party       $ 7,700,000          
Judicial Ruling [Member] | CRG Loan Agreement, Texas Case [Member] | CRG [Member] | Term Loan Agreement [Member]                  
Repayments of Debt             59,000,000   $ 59,000,000
Judicial Ruling [Member] | CRG Loan Agreement, Texas Case [Member] | Maximum [Member]                  
Loss Contingency, Damages Awarded, Value             $ 66,000,000 $ 66,000,000  
Pending Litigation [Member] | CRG Loan Agreement, Texas Case [Member]                  
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration         $ 4,100,000        
Loss Contingency, Damages Awarded,Value, Requested Modified Amount         $ 2,900,000        
Pending Litigation [Member] | CRG Loan Agreement, Ohio Case [Member]                  
Loss Contingency, Damages Sought, Value $ 4,100,000                
Pending Litigation [Member] | Platinum-Montaur Life Sciences LLC Litigation [Member]                  
Loss Contingency, Damages Sought, Value           $ 1,900,000