Note 14 - Segments - Segment Information (Details) - USD ($) |
3 Months Ended | 9 Months Ended | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sep. 30, 2021 |
Jun. 30, 2021 |
Mar. 31, 2021 |
Sep. 30, 2020 |
Jun. 30, 2020 |
Mar. 31, 2020 |
Sep. 30, 2021 |
Sep. 30, 2020 |
Dec. 31, 2020 |
|||||||||||||
Revenue from contract with customer | $ 9,000 | $ 7,000 | $ 45,000 | $ 31,000 | |||||||||||||||||
Grant and other revenue | 87,266 | 261,616 | 436,500 | 664,848 | |||||||||||||||||
Revenues, Total | 96,382 | 268,389 | 481,165 | 695,762 | |||||||||||||||||
Research and development expenses | 1,048,786 | 1,377,998 | 3,769,596 | 3,659,046 | |||||||||||||||||
Selling, general and administrative expenses, excluding depreciation and amortization | [1] | 1,451,309 | 1,773,532 | 5,077,058 | 4,894,778 | ||||||||||||||||
Depreciation, Depletion and Amortization, Nonproduction, Total | [2] | 18,066 | 15,402 | 55,672 | 51,501 | ||||||||||||||||
Loss from operations | (2,421,779) | [3] | (2,898,625) | [3] | (8,421,161) | [3] | (7,910,611) | ||||||||||||||
Other expense (4) | [4] | (14) | (713) | ||||||||||||||||||
Income tax expense | (16,043) | 0 | (16,043) | 0 | |||||||||||||||||
Net loss | (2,437,836) | $ (2,674,040) | $ (2,966,892) | (2,899,338) | $ (2,325,619) | $ (2,673,608) | (8,078,768) | (7,898,566) | |||||||||||||
Total assets, net of depreciation and amortization | 8,959,546 | 8,959,546 | $ 7,758,018 | ||||||||||||||||||
Capital expenditures | 18,042 | 120,810 | 20,749 | 129,216 | |||||||||||||||||
Cost of revenue | 0 | 82 | 0 | 1,048 | |||||||||||||||||
Other income (4) | (14) | (713) | 358,436 | [4] | 12,045 | [4] | |||||||||||||||
UNITED STATES | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 8,742,603 | 5,879,053 | 8,742,603 | 5,879,053 | |||||||||||||||||
Non-US [Member] | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 216,943 | 116,782 | 216,943 | 116,782 | |||||||||||||||||
License [Member] | |||||||||||||||||||||
Revenue from contract with customer | 9,116 | 4,726 | 44,665 | 4,726 | |||||||||||||||||
Royalty [Member] | |||||||||||||||||||||
Revenue from contract with customer | 0 | 2,047 | 0 | 26,188 | |||||||||||||||||
Diagnostics Segment [Member] | |||||||||||||||||||||
Grant and other revenue | 87,266 | 106,729 | 436,500 | 381,103 | |||||||||||||||||
Revenues, Total | 96,382 | 113,502 | 481,165 | 412,017 | |||||||||||||||||
Research and development expenses | 906,677 | 1,251,383 | 3,359,190 | 3,402,160 | |||||||||||||||||
Selling, general and administrative expenses, excluding depreciation and amortization | [1] | 0 | 0 | 0 | 0 | ||||||||||||||||
Depreciation, Depletion and Amortization, Nonproduction, Total | [2] | 6,040 | 4,027 | 18,121 | 4,027 | ||||||||||||||||
Loss from operations | (816,335) | [3] | (1,268,605) | [3] | (2,896,146) | [3] | (2,995,218) | ||||||||||||||
Other expense (4) | [4] | 0 | 0 | ||||||||||||||||||
Income tax expense | (5,763) | (5,763) | |||||||||||||||||||
Net loss | (822,098) | (1,141,990) | (2,901,909) | (2,995,218) | |||||||||||||||||
Capital expenditures | 0 | 120,810 | 0 | 120,810 | |||||||||||||||||
Cost of revenue | 82 | 1,048 | |||||||||||||||||||
Other income (4) | [4] | 0 | 0 | ||||||||||||||||||
Diagnostics Segment [Member] | UNITED STATES | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 185,205 | 1,000 | 185,205 | 1,000 | |||||||||||||||||
Diagnostics Segment [Member] | Non-US [Member] | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 216,353 | 116,782 | 216,353 | 116,782 | |||||||||||||||||
Diagnostics Segment [Member] | License [Member] | |||||||||||||||||||||
Revenue from contract with customer | 9,116 | 4,726 | 44,665 | 4,726 | |||||||||||||||||
Diagnostics Segment [Member] | Royalty [Member] | |||||||||||||||||||||
Revenue from contract with customer | 2,047 | 26,188 | |||||||||||||||||||
Therapeutics Segment [Member] | |||||||||||||||||||||
Grant and other revenue | 0 | 154,887 | 0 | 283,745 | |||||||||||||||||
Revenues, Total | 0 | 154,887 | 0 | 283,745 | |||||||||||||||||
Research and development expenses | 142,109 | 126,615 | 410,406 | 256,886 | |||||||||||||||||
Selling, general and administrative expenses, excluding depreciation and amortization | [1] | 744 | 0 | 3,623 | (550) | ||||||||||||||||
Depreciation, Depletion and Amortization, Nonproduction, Total | [2] | 0 | 0 | 0 | 0 | ||||||||||||||||
Loss from operations | (142,853) | [3] | 28,272 | [3] | (414,029) | [3] | 27,409 | ||||||||||||||
Other expense (4) | [4] | 0 | 0 | ||||||||||||||||||
Income tax expense | (824) | (824) | |||||||||||||||||||
Net loss | (143,677) | 28,272 | (414,853) | 27,409 | |||||||||||||||||
Capital expenditures | 0 | 0 | 0 | 0 | |||||||||||||||||
Cost of revenue | 0 | 0 | |||||||||||||||||||
Other income (4) | [4] | 0 | 0 | ||||||||||||||||||
Therapeutics Segment [Member] | UNITED STATES | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 0 | 38,320 | 0 | 38,320 | |||||||||||||||||
Therapeutics Segment [Member] | Non-US [Member] | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 0 | 0 | 0 | 0 | |||||||||||||||||
Therapeutics Segment [Member] | License [Member] | |||||||||||||||||||||
Revenue from contract with customer | 0 | 0 | 0 | 0 | |||||||||||||||||
Therapeutics Segment [Member] | Royalty [Member] | |||||||||||||||||||||
Revenue from contract with customer | 0 | 0 | |||||||||||||||||||
Corporate Segment [Member] | |||||||||||||||||||||
Grant and other revenue | 0 | 0 | 0 | 0 | |||||||||||||||||
Revenues, Total | 0 | 0 | 0 | 0 | |||||||||||||||||
Research and development expenses | 0 | 0 | 0 | 0 | |||||||||||||||||
Selling, general and administrative expenses, excluding depreciation and amortization | [1] | 1,450,565 | 1,773,532 | 5,073,435 | 4,895,328 | ||||||||||||||||
Depreciation, Depletion and Amortization, Nonproduction, Total | [2] | 12,026 | 11,375 | 37,551 | 47,474 | ||||||||||||||||
Loss from operations | (1,462,591) | [3] | (1,784,907) | [3] | (5,110,986) | [3] | (4,942,802) | ||||||||||||||
Other expense (4) | [4] | (14) | (713) | ||||||||||||||||||
Income tax expense | (9,457) | (9,457) | |||||||||||||||||||
Net loss | (1,472,062) | (1,785,620) | (4,762,007) | (4,930,757) | |||||||||||||||||
Capital expenditures | 18,042 | 0 | 20,749 | 8,406 | |||||||||||||||||
Cost of revenue | 0 | 0 | |||||||||||||||||||
Other income (4) | [4] | 358,436 | 12,045 | ||||||||||||||||||
Corporate Segment [Member] | UNITED STATES | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 8,557,398 | 5,839,733 | 8,557,398 | 5,839,733 | |||||||||||||||||
Corporate Segment [Member] | Non-US [Member] | |||||||||||||||||||||
Total assets, net of depreciation and amortization | 590 | 0 | 590 | 0 | |||||||||||||||||
Corporate Segment [Member] | License [Member] | |||||||||||||||||||||
Revenue from contract with customer | $ 0 | 0 | $ 0 | 0 | |||||||||||||||||
Corporate Segment [Member] | Royalty [Member] | |||||||||||||||||||||
Revenue from contract with customer | $ 0 | $ 0 | |||||||||||||||||||
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