Quarterly report pursuant to Section 13 or 15(d)

Note 4 - Stock-based Compensation - Summary of Stock Option Activity (Details)

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Note 4 - Stock-based Compensation - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Outstanding, options (in shares) 702,805  
Outstanding, weighted average exercise price (in dollars per share) $ 4.42  
Outstanding, weighted average remaining contractual life (Year) 8 years 2 months 12 days 5 years 6 months
Outstanding, aggregate intrinsic value $ 0 $ 0
Granted, options (in shares) 1,339,500  
Granted, weighted average exercise price (in dollars per share) $ 0.32  
Cancelled/Forfeited, options (in shares) (138,350)  
Cancelled/Forfeited, weighted average exercise price (in dollars per share) $ 1.04  
Expired, options (in shares) (850)  
Expired, weighted average exercise price (in dollars per share) $ 61.60  
Outstanding, options (in shares) 1,903,105 702,805
Outstanding, weighted average exercise price (in dollars per share) $ 1.75 $ 4.42
Exercisable, options (in shares) 569,231  
Exercisable, weighted average exercise price (in dollars per share) $ 4.92  
Exercisable, weighted average remaining contractual life (Year) 4 years 6 months  
Exercisable, aggregate intrinsic value $ 0