Annual report pursuant to Section 13 and 15(d)

Note 4 - Revenue From Contracts With Customers (Details Textual)

v3.19.1
Note 4 - Revenue From Contracts With Customers (Details Textual) - USD ($)
12 Months Ended
Dec. 31, 2018
Jan. 01, 2018
Dec. 31, 2017
Cumulative Effect of New Accounting Principle in Period of Adoption     $ (700,000)
Revenue from Contract with Customer, Including Assessed Tax $ 338,000    
Contract with Customer, Asset, Impairment Loss $ 0    
Contract with Customer, Payment Term, Minimum 15 days    
Contract with Customer, Payment Term, Maximum 90 days    
Contract with Customer, Asset, Net, Total $ 12,000    
Contract with Customer, Transaction Price of Royalties Using Expected Value Method 0    
Capitalized Contract Cost, Net, Total $ 0    
INDIA      
Contract with Customer, Term of Contract 8 years    
CHINA      
Contract with Customer, Term of Contract 10 years    
Long-term Contract with Customer [Member]      
Contract with Customer, Performance Obligation Satisfied in Previous Period $ 0    
Retained Earnings [Member]      
Cumulative Effect of New Accounting Principle in Period of Adoption     $ (700,000)
Accounting Standards Update 2014-09 [Member] | Sayre Pharmaceuticals [Member]      
Cumulative Effect of New Accounting Principle in Period of Adoption   $ 700,000  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member]      
Cumulative Effect of New Accounting Principle in Period of Adoption   (700,000)  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Sayre Pharmaceuticals [Member]      
Cumulative Effect of New Accounting Principle in Period of Adoption   (100,000)  
Accounting Standards Update 2014-09 [Member] | Retained Earnings [Member] | Beijing Sinotau Medical Research Co., Ltd. [Member]      
Cumulative Effect of New Accounting Principle in Period of Adoption   $ (600,000)