Current report filing

Note 18 - Income Taxes (Tables)

v3.8.0.1
Note 18 - Income Taxes (Tables)
12 Months Ended
Dec. 31, 2016
Notes Tables  
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
   
As of December 31,
 
   
2016
   
2015
 
Deferred tax assets:
               
Net operating loss carryforwards
  $
66,150,646
    $
60,129,827
 
R&D credit carryforwards
   
9,729,673
     
9,465,900
 
Stock compensation
   
1,368,458
     
1,898,394
 
Intangibles
   
1,720,761
     
1,921,934
 
Temporary differences
   
132,476
     
801,002
 
Deferred tax assets before valuation allowance
   
79,102,014
     
74,217,057
 
Valuation allowance
   
(79,102,014
)
   
(74,217,057
)
Net deferred tax assets
  $
    $
 
Summary of Tax Credit Carryforwards [Table Text Block]
       
As of December 31, 2016
 
Generated
 
Expiration
 
U.S. Net
Operating
Loss
Carryforwards
   
U.S. R&D
Credit
Carryforwards
 
1998
 
2018
  $
17,142,781
    $
1,173,387
 
1999
 
2019
   
     
130,359
 
2000
 
2020
   
     
71,713
 
2001
 
2021
   
     
39,128
 
2002
 
2022
   
1,282,447
     
5,350
 
2003
 
2023
   
337,714
     
2,905
 
2004
 
2024
   
1,237,146
     
22,861
 
2005
 
2025
   
2,999,083
     
218,332
 
2006
 
2026
   
3,049,735
     
365,541
 
2007
 
2027
   
2,842,078
     
342,898
 
2008
 
2028
   
2,777,503
     
531,539
 
2009
 
2029
   
13,727,950
     
596,843
 
2010
 
2030
   
5,397,680
     
1,094,449
 
2011
 
2031
   
1,875,665
     
1,950,744
 
2012
 
2032
   
28,406,659
     
468,008
 
2013
 
2033
   
37,450,522
     
681,772
 
2014
 
2034
   
34,088,874
     
816,116
 
2015
 
2035
   
25,073,846
     
492,732
 
2016
 
2036
   
15,581,209
     
358,404
 
Total carryforwards
  $
193,270,891
    $
9,363,081
 
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
   
Years Ended December 31,
 
   
2016
   
2015
   
2014
 
   
Amount
   
%
   
Amount
   
%
   
Amount
   
%
 
Benefit at statutory rate
  $
(2,508,264
)
   
(34.0
)%
  $
(7,835,163
)
   
(34.0
)%
  $
(10,322,016
)
   
(34.0
)%
Adjustments to valuation allowance
   
2,354,656
     
31.9
%
   
8,212,163
     
35.7
%
   
11,046,650
     
36.4
%
Adjustments to R&D credit carryforwards
   
(239,049
)
   
(3.2
)%
   
(612,087
)
   
(2.7
)%
   
(340,886
)
   
(1.1
)%
Disqualified debt interest
   
188,060
     
2.5
%
   
438,007
     
1.9
%
   
     
0.0
%
Permanent items and other
   
204,597
     
2.8
%
   
(202,920
)
   
(0.9
)%
   
(383,748
)
   
(1.3
)%
Benefit per financial statements
  $
     
 
    $
 
   
 
    $