Current report filing

Note 13 - Notes Payable (Details Textual)

v3.8.0.1
Note 13 - Notes Payable (Details Textual)
1 Months Ended 8 Months Ended 12 Months Ended
Mar. 03, 2017
USD ($)
Jul. 01, 2016
Jun. 22, 2016
USD ($)
May 31, 2016
USD ($)
shares
Mar. 31, 2014
USD ($)
$ / shares
shares
Dec. 31, 2016
USD ($)
$ / shares
Jul. 31, 2016
USD ($)
shares
Jul. 31, 2015
USD ($)
May 31, 2015
USD ($)
$ / shares
Mar. 31, 2014
USD ($)
$ / shares
shares
Jun. 30, 2013
USD ($)
$ / shares
shares
Dec. 31, 2015
USD ($)
Dec. 31, 2016
USD ($)
$ / shares
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Jun. 25, 2013
USD ($)
Feb. 28, 2017
Jul. 31, 2014
USD ($)
Jul. 31, 2012
USD ($)
Repayments of Notes Payable                         $ 231,453 $ 30,333,333 $ 25,000,000          
Change in Fair Value of Financial Instruments                         2,858,524 (614,782) (1,342,389)          
Interest Payable, Current           $ 5,756,519           $ 478 $ 5,756,519 478            
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares [1]           $ 0.33             $ 0.33              
Debt Instrument, Unamortized Discount           $ 0           2,033,506 $ 0 2,033,506            
Gain (Loss) on Extinguishment of Debt                         (2,440,714) (2,610,196)          
Equity Method Investment, Payment Upon Termination of Joint Venture                         110,000          
Interest Expense, Debt                         5,000 1,300,000 3,400,000          
Interest Expense Recorded Related to Amortization of Debt Discounts and Deferred Financing Costs                           326,000 844,000          
Disposal Group, Including Discontinued Operation, Interest Expense                         14,856,404 5,603,820 326,337          
Long-term Debt, Maturities, Repayments of Principal in Next Twelve Months           52,000,000             52,000,000              
Long-term Debt, Maturities, Repayments of Principal in Year Two           0             0              
Long-term Debt, Maturities, Repayments of Principal in Year Three           0             0              
Long-term Debt, Maturities, Repayments of Principal in Year Four           0             0              
Long-term Debt, Maturities, Repayments of Principal in Year Five           9,500,000             9,500,000              
Long-term Debt, Maturities, Repayments of Principal after Year Five           $ 0             $ 0              
R-NAV [Member]                                        
Repayments of Notes Payable             $ 333,333 $ 333,333                        
Debt Instrument, Face Amount                                     $ 666,666  
Equity Method Investment, Payment Upon Termination of Joint Venture       $ 110,000     110,000                          
Equity Method Investment, Forgiven Promissory Note, Amount       $ 333,333     $ 333,333                          
R-NAV [Member] | Preferred Stock [Member]                                        
Equity Method Investment, Shares Transferred Upon Termination of Joint Venture | shares       1,500,000     1,500,000                          
R-NAV [Member] | Common Stock [Member]                                        
Equity Method Investment, Shares Transferred Upon Termination of Joint Venture | shares       3,500,000     3,500,000                          
Series KK Warrants [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares         $ 1.918 $ 1.918       $ 1.918     $ 1.918              
Series HH Warrants [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares           2.49             2.49              
CRG Loan Agreement, Ohio Case [Member]                                        
Release of Cash Held in Escrow $ 2,000,000                                      
CRG Loan Agreement, Texas Case [Member]                                        
Release of Cash Held in Escrow 3,000,000                                      
Minimum [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares           0.01             0.01              
Maximum [Member]                                        
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares           $ 3.04             $ 3.04              
Subsequent Event [Member] | CRG Loan Agreement, Ohio Case [Member]                                        
Release of Cash Held in Escrow 2,000,000                                      
Subsequent Event [Member] | CRG Loan Agreement, Texas Case [Member]                                        
Release of Cash Held in Escrow 3,000,000                                      
Federal Funds Rate [Member] | R-NAV [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage                                     0.31%  
Platinum-Montaur Life Sciences LLC Litigation [Member]                                        
Line of Credit Facility, Maximum Borrowing Capacity                                       $ 50,000,000
Line of Credit Facility, Current Borrowing Capacity                     $ 35,000,000                 35,000,000
Line of Credit Facility, Increase Additional Borrowings Terms Not Negotiated           $ 15,000,000             $ 15,000,000             15,000,000
Proceeds from Lines of Credit                         0 4,500,000 0 $ 4,000,000 $ 8,000,000      
Debt Instrument, Interest Rate, Stated Percentage         10.00%       10.00% 10.00% 10.00%                  
InterestRateInAdditionToAmendedAgreement                     0.125%                  
Percentage of VWAP for Conversion Calculation                     90.00%                  
Period of Preceding Date of Conversion Request                     10 days                  
Minimum Revenue from Sales and Licensing for Mandatory Repayment Due                     $ 2,000,000                  
Repayments of Notes Payable                     $ 4,800,000                  
Stock for Stock Conversion Number of Shares Converted | shares                     2,364.9                  
Number of Common Shares Underlying Series B Preferred Stock | shares                     7,733,223                  
Shares Conversion, Number of Common Stock Equivalent to Each Preferred Stock | shares                     3,270                  
Debt Instrument, Convertible, Threshold Trading Days                 10                      
Debt Instrument, Convertible, Stock Price Trigger | $ / shares                 $ 2.53                      
Embedded Derivative, Fair Value of Embedded Derivative Liability           153,000             153,000              
Change in Fair Value of Financial Instruments                         2,900,000 (615,000) (1,300,000)          
Convertible Debt, Fair Value Disclosures           9,600,000           11,500,000 9,600,000 11,500,000            
Interest Expense, Debt, Excluding Amortization                         1,000,000 761,000            
Line of Credit Facility, Decrease Forgiveness Interest Percentage   6.00%                                    
Notes Payable           9,500,000             9,500,000              
Long-term Line of Credit           7,700,000             7,700,000              
Interest Payable, Current           1,800,000             1,800,000              
Line of Credit Facility, Remaining Borrowing Capacity           27,300,000             27,300,000              
Platinum-Montaur Life Sciences LLC Litigation [Member] | Prime Rate [Member]                                        
Debt Instrument, Basis Spread on Variable Rate                 6.75% 6.75% 6.75%                  
Platinum-Montaur Life Sciences LLC Litigation [Member] | Oxford Financing Rate [Member]                                        
Debt Instrument, Basis Spread on Variable Rate         0.125%                              
Platinum-Montaur Life Sciences LLC Litigation [Member] | Interest Rate Pursuant to CRG Term Loan [Member]                                        
Debt Instrument, Basis Spread on Variable Rate                 0.125%                      
Platinum Loan Agreement [Member] | PPCO [Member]                                        
Line of Credit Facility, Maximum Borrowing Capacity                                       $ 50,000,000
Debt Instrument, Interest Rate, Stated Percentage   8.125%                                    
Convertible Debt, Fair Value Disclosures           153,000           3,000,000 153,000 3,000,000            
Repayments of Debt 7,700,000                                      
Convertible Debt 1,900,000                                      
Platinum Loan Agreement [Member] | PPCO [Member] | Subsequent Event [Member]                                        
Repayments of Debt 7,700,000                                      
Convertible Debt 1,900,000                                      
Term Loan Agreement [Member] | Cardinal Health 414 [Member]                                        
Letters of Credit Outstanding, Amount 7,000,000                                      
Term Loan Agreement [Member] | CRG [Member]                                        
Letters of Credit Outstanding, Amount 12,000,000                                      
Term Loan Agreement [Member] | Subsequent Event [Member] | Cardinal Health 414 [Member]                                        
Letters of Credit Outstanding, Amount 7,000,000                                      
Term Loan Agreement [Member] | Subsequent Event [Member] | CRG [Member]                                        
Letters of Credit Outstanding, Amount 12,000,000                                      
Debt Instrument, Final Payoff Amount, Threshold Above Which the Reporting Entity Will First Pay Without Resorting to Letter of Credit 59,000,000                                      
Term Loan Agreement [Member] | CRG [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage                 14.00%                      
Interest Expense, Debt, Excluding Amortization                         553,000 1,300,000            
Notes Payable           51,700,000           51,300,000 51,700,000 51,300,000            
Debt Instrument, Face Amount                 $ 50,000,000                      
Debt Instrument, Additional Loans That May Be Made Available Upon the Satisfaction of Certain Conditions                 $ 10,000,000                      
Percentage of Per Annum Interest Paying in Cash                 10.00%                      
Percentage of Per Annum Interest as Compounded Interest                 4.00%                      
Debt Instrument, Number of Quarterly Payments                 8                      
Debt Instrument Payment Terms Payment Period                 2 years                      
Debt Instrument, Unamortized Discount (Premium), Net                 $ 2,200,000                      
Debt Instrument End of Term Fee, Amount                 1,000,000                      
Debt Instrument, Fee Amount                 1,000,000                      
Debt Instrument, Covenant Compliance, Income (Loss) Earnings Before Interest, Taxes, Depreciation, and Amortization, Minimum                 5,000,000                      
Debt Instrument, Covenant Compliance Sales Revenue Minimum Next Twelve Months           22,500,000             22,500,000              
DebtInstrumentCovenantComplianceTargetRevenueMinimum                 $ 45,000,000                      
Debt Instrument, Covenant Compliance Cure Right Ratio                 2.5                      
Debt Instrument, Covenant Compliance Liquidity Minimum                 $ 5,000,000                      
Debt Instrument, Interest Rate in the Event of Default                 18.00%                      
Primary Bank Account Cash Taken Possession Of By Creditor     $ 4,100,000                                  
Payments to Prepayment Premium and Backend Facility Fee on Claims of Default     3,900,000                                  
Payments to Principal Balance of Debt on Claims of Default     $ 189,000                                  
Debt Instrument, Final Payoff Amount, Threshold Above Which the Reporting Entity Will First Pay Without Resorting to Letter of Credit 59,000,000                                      
Term Loan Agreement [Member] | CRG [Member] | Maximum [Member]                                        
Debt Instrument, Agreed-upon Final Payoff Amount 66,000,000                                      
Term Loan Agreement [Member] | CRG [Member] | Subsequent Event [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage                                   14.00%    
Repayments of Debt 59,000,000                                      
Debt Instrument, Final Payoff Amount, Threshold Above Which the Reporting Entity Will First Pay Without Resorting to Letter of Credit 59,000,000                                      
Term Loan Agreement [Member] | CRG [Member] | Subsequent Event [Member] | Minimum [Member]                                        
Debt Instrument, Agreed-upon Final Payoff Amount 47,000,000                                      
Term Loan Agreement [Member] | CRG [Member] | Subsequent Event [Member] | Maximum [Member]                                        
Debt Instrument, Agreed-upon Final Payoff Amount $ 66,000,000                                      
Term Loan Agreement [Member] | CRG [Member] | Accrued Liabilities and Other [Member]                                        
Interest Payable, Current           $ 5,800,000           0 $ 5,800,000 0            
Oxford Finance, LLC [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage         8.50%         8.50%                    
Debt Instrument, Face Amount         $ 30,000,000         $ 30,000,000                    
Debt Instrument, Unamortized Discount (Premium), Net         3,000,000         3,000,000                    
Debt Instrument End of Term Fee, Amount                   2,400,000   2,400,000                
Repayments of Long-term Debt                 $ 31,700,000                      
Debt Instrument, Early Redemption Fee Amount                 $ 289,000                      
Long-term Debt, Gross                       $ 0   $ 0            
Oxford Finance, LLC [Member] | Series KK Warrants [Member]                                        
Debt Instrument, Unamortized Discount (Premium), Net         $ 120,000         $ 120,000                    
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares         391,032         391,032                    
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares         $ 1.918         $ 1.918                    
GECC/MidCap Financial SBIC LP [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage                     9.83%                  
Debt Instrument, Face Amount                     $ 25,000,000                  
Debt Instrument End of Term Fee, Amount                   $ 1,000,000 $ 1,000,000                  
Repayments of Long-term Debt                   26,700,000                    
Debt Instrument, Early Redemption Fee Amount         $ 500,000         500,000                    
Long-term Debt, Gross                             $ 0          
Number of Monthly Installment Payments on Notes Payable                     30                  
Percentage of Original Principal Amount of Loan to Be Paid as Fee                     4.00%                  
Debt Instrument, Unamortized Discount                     $ 881,000                  
Gain (Loss) on Extinguishment of Debt                   $ 2,600,000                    
GECC/MidCap Financial SBIC LP [Member] | Series HH Warrants [Member]                                        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares                     301,205                  
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares                     $ 2.49                  
Debt Instrument, Unamortized Discount                     $ 1,900,000                  
Notes Payable Issued for Prepayment of Insurance Premiums [Member] | IPFS [Member]                                        
Debt Instrument, Interest Rate, Stated Percentage           8.99%             8.99%              
Debt Instrument, Face Amount           $ 348,000             $ 348,000              
Debt Instrument, Term           240 days                            
Debt Instrument, Periodic Payment           $ 45,000                            
[1] Weighted average exercise price.