Note 18 - Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) |
Dec. 31, 2016 |
Dec. 31, 2015 |
|---|---|---|
| Deferred tax assets: | ||
| Net operating loss carryforwards | $ 66,150,646 | $ 60,129,827 |
| R&D credit carryforwards | 9,729,673 | 9,465,900 |
| Stock compensation | 1,368,458 | 1,898,394 |
| Intangibles | 1,720,761 | 1,921,934 |
| Temporary differences | 132,476 | 801,002 |
| Deferred tax assets before valuation allowance | 79,102,014 | 74,217,057 |
| Valuation allowance | (79,102,014) | (74,217,057) |
| Net deferred tax assets |
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to research and development tax credit carryforwards. No definition available.
|
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to temporary differences. No definition available.
|
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill. No definition available.
|
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
|
| X | ||||||||||
- References No definition available.
|
| X | ||||||||||
- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2003/role/presentationRef
|
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
|
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
|
| X | ||||||||||
- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/presentationRef
|