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Note 18 - Income Taxes - Reconciliations Between the Statutory Federal Income Tax Rate and the Effective Tax Rate (Details)

v3.8.0.1
Note 18 - Income Taxes - Reconciliations Between the Statutory Federal Income Tax Rate and the Effective Tax Rate (Details) - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Benefit at statutory rate, amount $ (2,508,264) $ (7,835,163) $ (10,322,016)
Benefit at statutory rate, percent (34.00%) (34.00%) (34.00%)
Adjustments to valuation allowance, amount $ 2,354,656 $ 8,212,163 $ 11,046,650
Adjustments to valuation allowance, percent 31.90% 35.70% 36.40%
Adjustments to R&D credit carryforwards, amount $ (239,049) $ (612,087) $ (340,886)
Adjustments to R&D credit carryforwards, percent (3.20%) (2.70%) (1.10%)
Disqualified debt interest, amount $ 188,060 $ 438,007
Disqualified debt interest, percent 2.50% 1.90% 0.00%
Permanent items and other, amount $ 204,597 $ (202,920) $ (383,748)
Permanent items and other, percent 2.80% (0.90%) (1.30%)
Benefit per financial statements, amount