Quarterly report pursuant to Section 13 or 15(d)

Note 2 - Liquidity (Details Textual)

Note 2 - Liquidity (Details Textual) - USD ($)									1 Months Ended
Note 2 - Liquidity (Details Textual) - USD ($)	Apr. 12, 2018	Apr. 09, 2018	Apr. 02, 2018	Mar. 26, 2018	Jan. 16, 2018	Nov. 02, 2017	Mar. 31, 2017	Mar. 03, 2017	Dec. 31, 2017	Mar. 31, 2017
Subsequent Event [Member] \| CRG [Member]
Draws on Letter of Credit		$ 7,100,000
Sale of Assets to Cardinal Health 414 [Member] \| Subsequent Event [Member]
Sale of Assets, Cash Received from Buyer as Result of Amendment			$ 6,000,000
Sale of Assets, Maximum Amount Receivable from Buyer for Unused Portion of Letter of Credit			$ 7,100,000
PPCO [Member] \| Platinum Loan Agreement [Member]
Repayments of Debt								$ 7,700,000
Convertible Debt, Total								1,900,000
Judicial Ruling [Member] \| CRG Loan Agreement, Texas Case [Member]
Loss Contingency, Damages Awarded, Value, Additional Amount								7,000,000	$ 7,000,000
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration					$ 4,100,000				4,100,000
Loss Contingency, Damages Awarded,Value, Requested Modified Amount					2,900,000
Judicial Ruling [Member] \| CRG Loan Agreement, Texas Case [Member] \| Surety Bond [Member]
Loss Contingency, Amount Awarded to Other Party				$ 7,700,000
Judicial Ruling [Member] \| CRG Loan Agreement, Texas Case [Member] \| CRG [Member] \| Term Loan Agreement [Member]
Repayments of Debt							$ 59,000,000	59,000,000		$ 59,000,000
Judicial Ruling [Member] \| CRG Loan Agreement, Texas Case [Member] \| Maximum [Member]
Loss Contingency, Damages Awarded, Value								$ 66,000,000	$ 66,000,000
Pending Litigation [Member] \| CRG Loan Agreement, Texas Case [Member]
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration					4,100,000
Loss Contingency, Damages Awarded,Value, Requested Modified Amount					$ 2,900,000
Pending Litigation [Member] \| CRG Loan Agreement, Ohio Case [Member] \| Subsequent Event [Member]
Loss Contingency, Damages Sought, Value	$ 4,100,000
Pending Litigation [Member] \| Platinum-Montaur Life Sciences LLC Litigation [Member]
Loss Contingency, Damages Sought, Value						$ 1,900,000