Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Stockholders' Equity (Deficit)

Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)	Preferred Stock [Member] Series C Preferred Stock [Member]	Preferred Stock [Member] Series D Preferred Stock [Member]	Preferred Stock Subscription [Member] Series D Preferred Stock [Member]	Preferred Stock Subscription [Member]	Preferred Stock Subscriptions Receivable [Member] Series D Preferred Stock [Member]	Preferred Stock Subscriptions Receivable [Member]	Common Stock [Member] Private Placement [Member]	Common Stock [Member] Series C Preferred Stock [Member]	Common Stock [Member] Series D Preferred Stock [Member]	Common Stock [Member]	Common Stock Subscription [Member] Private Placement [Member]	Common Stock Subscription [Member]	Common Stock Subscriptions Receivable [Member] Private Placement [Member]	Common Stock Subscriptions Receivable [Member]	Additional Paid-in Capital [Member] Private Placement [Member]	Additional Paid-in Capital [Member] Series C Preferred Stock [Member]	Additional Paid-in Capital [Member] Series D Preferred Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member] Series C Preferred Stock [Member]	Retained Earnings [Member] Series D Preferred Stock [Member]	Retained Earnings [Member]	Noncontrolling Interest [Member]	AOCI Attributable to Parent [Member]	Private Placement [Member]	Series C Preferred Stock [Member]	Series D Preferred Stock [Member]	Total
Balance (in shares) at Dec. 31, 2018										10,019,535
Balance at Dec. 31, 2018										$ 200,391								$ 338,265,383			$ (336,722,905)	$ 668,321	$ (730)				$ 2,410,460
Issued restricted stock (in shares)										15,000
Issued restricted stock										$ 300																	300
Issued stock (in shares)							1,173,411			8,000,000
Issued stock							$ 1,513			$ 8,000					$ 1,088,487			5,158,441						$ 1,090,000			5,166,441
Adjustments related to reverse stock split (in shares)										(1,114)
Adjustments related to reverse stock split																		(3,385)									$ (3,385)
Issued stock to 401(k) plan (in shares)										8,128																	8,128
Issued stock to 401(k) plan										$ 8								19,580									$ 19,588
Value of warrants issued in connection with public offering																		261,288									261,288
Issued stock in payment of services (in shares)										20,000
Issued stock in payment of services										$ 20								14,780									14,800
Stock subscribed in connection with private placement (in shares)												902,162
Stock subscribed in connection with private placement												$ 902						811,044									811,946
Change in estimated fair value of MT warrants																						63,000					63,000
Stock compensation expense																		232,058									232,058
Net loss																					(10,948,197)	(17)					(10,948,214)
Unrealized gain on available-for-sale securities																							$ 730				730
Total comprehensive loss																											$ (10,947,484)
Issued stock in payment of employee bonuses (in shares)																											8,128
Issued stock																											$ (841,559)
Issued restricted stock										$ 300																	300
Balance (in shares) at Dec. 31, 2019										19,234,960		902,162
Balance at Dec. 31, 2019										$ 210,232		$ 902						345,847,676			(347,671,102)	731,303					(880,989)
Issued restricted stock										$ 60																	60
Issued stock (in shares)	420,000	17,750					3,280,691			1,647,059	(902,162)
Issued stock	$ 420	$ 18					$ 3,281			$ 1,647	$ (902)					$ 4,162,758	$ 132,089	1,248,353						2,059	$ 4,163,178	$ 132,107	$ 1,250,000
Issued stock to 401(k) plan (in shares)										32,651																	32,651
Issued stock to 401(k) plan										$ 33								39,801									$ 39,834
Issued stock in payment of services (in shares)										23,810
Issued stock in payment of services										$ 24								70,177									70,201
Stock subscribed in connection with private placement (in shares)			132,250								995,000
Stock subscribed in connection with private placement			$ 132		(10,300,000)						$ 995		$ (4,975,000)		7,014,126		14,849,851							$ 2,040,121		4,549,983
Stock compensation expense																		230,522									230,522
Net loss																					(10,721,691)						(10,721,691)
Unrealized gain on available-for-sale securities
Total comprehensive loss																											$ (10,721,691)
Issued stock in payment of employee bonuses (in shares)										94,159																	32,651
Issued stock in payment of employee bonuses										$ 94								171,428									$ 171,522
Issued stock															$ (320)
Issued restricted stock (in shares)										60,000
Issued restricted stock										$ 60																	60
Issued stock upon exercise of warrants (in shares)										300,595
Issued stock upon exercise of warrants										$ 300								(300)
Deemed dividend																466,667	197,223		(466,667)	(197,223)
Issued stock upon conversion (in shares)	(420,000)	(17,750)						1,425,076	827,280
Issued stock upon conversion	$ (420)	$ (18)						$ 1,425	$ 827							(1,005)	$ (809)
Issued stock in payment of Series C Preferred Stock fees (in shares)								14,205		209,205
Issued stock in payment of Series C Preferred Stock fees								$ 14								$ (14)
Issued stock pursuant to Jubilant MOU										$ 209								999,791									1,000,000
Balance (in shares) at Dec. 31, 2020				132,250						27,149,691		995,000
Balance at Dec. 31, 2020				$ 132		$ (10,300,000)				$ 218,146		$ 995		$ (4,975,000)				$ 375,428,014			$ (359,056,683)	$ 731,303					$ 2,046,907