Annual report pursuant to Section 13 and 15(d)

Note 13 - Commitments and Contingencies (Details Textual)

Note 13 - Commitments and Contingencies (Details Textual)								1 Months Ended			2 Months Ended	12 Months Ended
	Mar. 16, 2021 USD ($)	Nov. 27, 2019 USD ($)	Apr. 26, 2019	Aug. 14, 2018	Apr. 09, 2018 USD ($)	Nov. 02, 2017 USD ($)	Mar. 03, 2017 USD ($)	Nov. 30, 2018 shares	Nov. 30, 2017 USD ($)	Jun. 30, 2016 USD ($)	Jan. 31, 2020 shares	Dec. 31, 2020 USD ($) shares	Dec. 31, 2019 USD ($) shares	Feb. 14, 2020 USD ($)	Aug. 31, 2018 shares
Stock Issued During Period, Shares, New Issues (in shares) \| shares											2,100,000
Stockholders' Equity Attributable to Parent, Ending Balance												$ 1,315,604	$ (1,612,292)
Market Capitalization, Fair Value												$ 58,400,000
Pro Forma [Member]
Stockholders' Equity Attributable to Parent, Ending Balance														$ 6,000,000
Common Stock [Member]
Stock Issued During Period, Shares, New Issues (in shares) \| shares												1,647,059	8,000,000
Former Chief Executive Officer and President [Member]
Common Stock Shares Provided by Agreement (in shares) \| shares															1,175,000
Common Stock Shares Provided by Agreement, Escrow Period (Month)				1 year 180 days
Former Chief Executive Officer and President [Member] \| Common Stock [Member]
Stock Issued During Period, Shares, New Issues (in shares) \| shares								925,000
Stock Issued During Period, Shares, New Issues Placed in Escrow (in shares) \| shares								250,000				250,000
Former Chief Executive Officer and President [Member] \| MT [Member] \| Common Stock [Member] \| Dr. Michael Goldberg [Member]
Ownership Percentage				5.00%
CRG [Member]
Draws on Letter of Credit					$ 7,100,000
CRG Loan Agreement, Texas Case [Member] \| Judicial Ruling [Member]
Loss Contingency, Damages Awarded, Value, Additional Amount							$ 7,000,000
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration										$ 4,100,000
Ohio Court of Common Pleas [Member]
Litigation Settlement, Amount Awarded from Other Party		$ 4,300,000
Ohio Court of Common Pleas [Member] \| Subsequent Event [Member]
Litigation Settlement, Reversal of Amount Awarded from Other Party	$ 4,300,000
Platinum-Montaur Life Sciences LLC Litigation [Member]
Loss Contingency, Damages Sought, Value									$ 1,900,000
Platinum-Montaur Life Sciences LLC Litigation [Member] \| Pending Litigation [Member]
Loss Contingency, Damages Sought, Value						$ 1,900,000
Maximum [Member] \| Before Reverse Stock Split [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio			20
CRG [Member] \| Term Loan Agreement [Member] \| CRG Loan Agreement, Texas Case [Member] \| Judicial Ruling [Member]
Repayments of Debt							59,000,000
CRG [Member] \| Term Loan Agreement [Member] \| Maximum [Member]
Debt Instrument, Agreed-upon Final Payoff Amount							$ 66,000,000