Segments (Details) - USD ($)
|
3 Months Ended |
12 Months Ended |
Dec. 31, 2016 |
Sep. 30, 2016 |
Jun. 30, 2016 |
Mar. 31, 2016 |
Dec. 31, 2015 |
Sep. 30, 2015 |
Jun. 30, 2015 |
Mar. 31, 2015 |
Dec. 31, 2016 |
Dec. 31, 2015 |
Dec. 31, 2014 |
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
$ 2,332,000
|
$ 6,690,000
|
$ 4,232,000
|
$ 3,783,000
|
$ 2,953,000
|
$ 3,503,000
|
$ 1,964,000
|
$ 1,835,000
|
$ 17,037,098
|
$ 10,254,352
|
$ 4,233,953
|
Lymphoseek license revenue |
0
|
1,296,000
|
246,000
|
254,000
|
550,000
|
250,000
|
250,000
|
83,000
|
1,795,625
|
1,133,333
|
300,000
|
Grant and other revenue |
1,023,000
|
511,000
|
917,000
|
686,000
|
477,000
|
541,000
|
654,000
|
190,000
|
3,136,983
|
1,861,622
|
1,740,896
|
Total revenue |
|
|
|
|
|
|
|
|
21,969,706
|
13,249,307
|
6,274,849
|
Cost of goods sold, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
2,192,902
|
1,654,800
|
|
Research and development expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
8,882,576
|
12,777,116
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
12,616,334
|
16,796,490
|
|
Depreciation and amortization |
|
|
|
|
|
|
|
|
501,369
|
571,419
|
|
Income (loss) from operations |
(2,433,000)
|
$ 3,358,000
|
$ (580,000)
|
$ (2,568,000)
|
(4,323,000)
|
$ (2,601,000)
|
$ (3,811,000)
|
$ (7,816,000)
|
(2,223,475)
|
(18,550,518)
|
(27,632,956)
|
Other income (expense), excluding equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
(12,070,397)
|
(9,902,424)
|
|
Equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
(15,159)
|
(305,253)
|
(523,809)
|
Benefit from income taxes |
|
|
|
|
|
|
|
|
0
|
436,051
|
0
|
Net loss from continuing operations |
|
|
|
|
|
|
|
|
|
(28,322,144)
|
|
Income from discontinued operations, net of tax effect |
|
|
|
|
|
|
|
|
0
|
758,609
|
0
|
Net income (loss) |
|
|
|
|
|
|
|
|
(14,309,031)
|
(27,563,535)
|
(35,726,669)
|
Total assets, net of depreciation and amortization |
12,461,676
|
|
|
|
14,964,513
|
|
|
|
12,461,676
|
14,964,513
|
|
Payments to Acquire Property, Plant, and Equipment |
|
|
|
|
|
|
|
|
1,847
|
39,001
|
$ 1,114,448
|
U S |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
16,982,234
|
10,229,659
|
|
Total assets, net of depreciation and amortization |
12,329,143
|
|
|
|
14,552,834
|
|
|
|
12,329,143
|
14,552,834
|
|
Non Us [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
54,864
|
24,693
|
|
Total assets, net of depreciation and amortization |
132,533
|
|
|
|
411,679
|
|
|
|
132,533
|
411,679
|
|
Diagnostics Segment [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek license revenue |
|
|
|
|
|
|
|
|
1,795,625
|
1,133,333
|
|
Grant and other revenue |
|
|
|
|
|
|
|
|
3,012,217
|
1,861,622
|
|
Total revenue |
|
|
|
|
|
|
|
|
21,844,940
|
13,249,307
|
|
Cost of goods sold, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
2,192,902
|
1,654,800
|
|
Research and development expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
8,120,425
|
12,046,221
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
3,652,154
|
5,852,214
|
|
Depreciation and amortization |
|
|
|
|
|
|
|
|
104,138
|
281,314
|
|
Income (loss) from operations |
|
|
|
|
|
|
|
|
7,775,321
|
(6,585,242)
|
|
Other income (expense), excluding equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
0
|
0
|
|
Equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
0
|
0
|
|
Benefit from income taxes |
|
|
|
|
|
|
|
|
|
0
|
|
Net loss from continuing operations |
|
|
|
|
|
|
|
|
|
(6,585,242)
|
|
Income from discontinued operations, net of tax effect |
|
|
|
|
|
|
|
|
|
0
|
|
Net income (loss) |
|
|
|
|
|
|
|
|
7,775,321
|
(6,585,242)
|
|
Payments to Acquire Property, Plant, and Equipment |
|
|
|
|
|
|
|
|
0
|
26,589
|
|
Diagnostics Segment [Member] | U S |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
16,982,234
|
10,229,659
|
|
Total assets, net of depreciation and amortization |
3,610,354
|
|
|
|
3,948,971
|
|
|
|
3,610,354
|
3,948,971
|
|
Diagnostics Segment [Member] | Non Us [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
54,864
|
24,693
|
|
Total assets, net of depreciation and amortization |
131,752
|
|
|
|
410,666
|
|
|
|
131,752
|
410,666
|
|
Therapeutics Segment [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek license revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Grant and other revenue |
|
|
|
|
|
|
|
|
124,766
|
0
|
|
Total revenue |
|
|
|
|
|
|
|
|
124,766
|
0
|
|
Cost of goods sold, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
0
|
0
|
|
Research and development expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
762,151
|
730,895
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
63,158
|
123,884
|
|
Depreciation and amortization |
|
|
|
|
|
|
|
|
0
|
0
|
|
Income (loss) from operations |
|
|
|
|
|
|
|
|
(700,543)
|
(854,779)
|
|
Other income (expense), excluding equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
0
|
0
|
|
Equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
0
|
0
|
|
Benefit from income taxes |
|
|
|
|
|
|
|
|
|
0
|
|
Net loss from continuing operations |
|
|
|
|
|
|
|
|
|
(854,779)
|
|
Income from discontinued operations, net of tax effect |
|
|
|
|
|
|
|
|
|
0
|
|
Net income (loss) |
|
|
|
|
|
|
|
|
(700,543)
|
(854,779)
|
|
Payments to Acquire Property, Plant, and Equipment |
|
|
|
|
|
|
|
|
0
|
0
|
|
Therapeutics Segment [Member] | U S |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Total assets, net of depreciation and amortization |
15,075
|
|
|
|
0
|
|
|
|
15,075
|
0
|
|
Therapeutics Segment [Member] | Non Us [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Total assets, net of depreciation and amortization |
0
|
|
|
|
0
|
|
|
|
0
|
0
|
|
Corporate Non Segment [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek license revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Grant and other revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Total revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Cost of goods sold, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
0
|
0
|
|
Research and development expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
0
|
0
|
|
Selling, general and administrative expenses, excluding depreciation and amortization |
|
|
|
|
|
|
|
|
8,901,022
|
10,820,392
|
|
Depreciation and amortization |
|
|
|
|
|
|
|
|
397,231
|
290,105
|
|
Income (loss) from operations |
|
|
|
|
|
|
|
|
(9,298,253)
|
(11,110,497)
|
|
Other income (expense), excluding equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
(12,070,397)
|
(9,902,424)
|
|
Equity in the loss of R-NAV, LLC |
|
|
|
|
|
|
|
|
(15,159)
|
(305,253)
|
|
Benefit from income taxes |
|
|
|
|
|
|
|
|
|
436,051
|
|
Net loss from continuing operations |
|
|
|
|
|
|
|
|
|
(20,882,123)
|
|
Income from discontinued operations, net of tax effect |
|
|
|
|
|
|
|
|
|
758,609
|
|
Net income (loss) |
|
|
|
|
|
|
|
|
(21,383,809)
|
(20,123,514)
|
|
Payments to Acquire Property, Plant, and Equipment |
|
|
|
|
|
|
|
|
1,847
|
12,412
|
|
Corporate Non Segment [Member] | U S |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Total assets, net of depreciation and amortization |
8,703,714
|
|
|
|
10,603,863
|
|
|
|
8,703,714
|
10,603,863
|
|
Corporate Non Segment [Member] | Non Us [Member] |
|
|
|
|
|
|
|
|
|
|
|
Segment Reporting Information [Line Items] |
|
|
|
|
|
|
|
|
|
|
|
Lymphoseek sales revenue |
|
|
|
|
|
|
|
|
0
|
0
|
|
Total assets, net of depreciation and amortization |
$ 781
|
|
|
|
$ 1,013
|
|
|
|
$ 781
|
$ 1,013
|
|