Annual report pursuant to Section 13 and 15(d)

Income Taxes (Schedule of Tax Rate Reconciliation) (Details)

v2.4.1.9
Income Taxes (Schedule of Tax Rate Reconciliation) (Details) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Amount      
Benefit at statutory rate $ (12,147,068)us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate $ (14,517,816)us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate $ (9,913,450)us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
Adjustments to valuation allowance 12,925,380us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance 15,399,021us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance 8,604,147us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
Adjustments to R&D credit carryforwards (340,886)us-gaap_IncomeTaxReconciliationTaxCreditsResearch (842,414)us-gaap_IncomeTaxReconciliationTaxCreditsResearch 1,064,623us-gaap_IncomeTaxReconciliationTaxCreditsResearch
Permanent items and other (437,426)us-gaap_IncomeTaxReconciliationOtherAdjustments (38,791)us-gaap_IncomeTaxReconciliationOtherAdjustments 244,680us-gaap_IncomeTaxReconciliationOtherAdjustments
Benefit per financial statements $ 0us-gaap_IncomeTaxExpenseBenefit $ 0us-gaap_IncomeTaxExpenseBenefit $ 0us-gaap_IncomeTaxExpenseBenefit
Percent      
Benefit at statutory rate (34.00%)us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate (34.00%)us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate (34.00%)us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
Adjustments to valuation allowance 36.20%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance 36.10%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance 29.50%us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
Adjustments to R&D credit carryforwards (1.00%)us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch (2.00%)us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch 3.70%us-gaap_EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
Permanent items and other (1.20%)us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments (0.10%)us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments 0.80%us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments