Agreements (Details) (USD $)
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12 Months Ended |
1 Months Ended |
36 Months Ended |
108 Months Ended |
Dec. 31, 2014
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Dec. 31, 2013
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Dec. 31, 2012
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Nov. 30, 2009
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May 31, 2013
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Aug. 31, 2013
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Sep. 30, 2013
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Jan. 31, 2002
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Apr. 30, 2008
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Jul. 31, 2014
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Dec. 31, 2011
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Jul. 31, 2012
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Dec. 31, 2004
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Dec. 31, 2014
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Agreements [Line Items] |
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Research and development |
$ 16,779,589us-gaap_ResearchAndDevelopmentExpense
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$ 23,710,183us-gaap_ResearchAndDevelopmentExpense
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$ 16,890,482us-gaap_ResearchAndDevelopmentExpense
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Common Stock, shares issued |
150,200,259us-gaap_CommonStockSharesIssued
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135,919,423us-gaap_CommonStockSharesIssued
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150,200,259us-gaap_CommonStockSharesIssued
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Reliable Supply Agreement [Member] |
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Agreements [Line Items] |
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Purchases under manufacture and supply agreement |
300,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_ReliableSupplyAgreementMember
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666,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_ReliableSupplyAgreementMember
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939,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_ReliableSupplyAgreementMember
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Purchase orders issued |
0navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_ReliableSupplyAgreementMember
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0navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_ReliableSupplyAgreementMember
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Initial term |
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10 years
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Resolution term |
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60 days
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Nordion Supply Agreement [Member] |
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Agreements [Line Items] |
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Purchases under manufacture and supply agreement |
505,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_NordionSupplyAgreementMember
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771,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_NordionSupplyAgreementMember
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Purchase orders issued |
317,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_NordionSupplyAgreementMember
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317,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_NordionSupplyAgreementMember
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Initial term |
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3 years
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Resolution term |
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30 days
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Notice period |
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180 days
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PETNET Supply Agreement [Member] |
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Agreements [Line Items] |
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Purchases under manufacture and supply agreement |
2,200,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_PETNETSupplyAgreementMember
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1,400,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_PETNETSupplyAgreementMember
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Purchase orders issued |
132,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_PETNETSupplyAgreementMember
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132,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_PETNETSupplyAgreementMember
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Initial term |
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3 years
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Resolution term |
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30 days
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Notice period |
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60 days
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Automatic renewal date |
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1 year
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OsoBio Supply Agreement [Member] |
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Agreements [Line Items] |
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Purchases under manufacture and supply agreement |
96,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_OsoBioSupplyAgreementMember
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1,200,000navb_PurchasesUnderCommitment / navb_AgreementsByTypeAxis = navb_OsoBioSupplyAgreementMember
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Purchase orders issued |
463,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_OsoBioSupplyAgreementMember
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463,000navb_PurchaseOrdersIssued / navb_AgreementsByTypeAxis = navb_OsoBioSupplyAgreementMember
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Resolution term |
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60 days
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Notice period |
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12 months
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Automatic renewal date |
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2 years
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Lymphoseek License Agreement [Member] |
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Agreements [Line Items] |
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License fee |
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25,000us-gaap_LicenseCosts / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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License maintenance fee |
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25,000navb_LicenseMaintenanceFee / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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Minimum annual royalty |
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25,000navb_MinimumAnnualRoyalty / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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Research and development |
353,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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273,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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33,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekLicenseAgreementMember
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Lymphoseek Expanded License Agreement [Member] |
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Agreements [Line Items] |
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License fee |
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25,000us-gaap_LicenseCosts / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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License maintenance fee |
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25,000navb_LicenseMaintenanceFee / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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Minimum annual royalty |
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25,000navb_MinimumAnnualRoyalty / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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Research and development |
25,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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29,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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31,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_LymphoseekExpandedLicenseAgreementMember
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Tilmanocept License Agreement [Member] [Domain] |
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Agreements [Line Items] |
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License fee |
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25,000us-gaap_LicenseCosts / navb_AgreementsByTypeAxis = navb_TilmanoceptLicenseAgreementMemberDomain
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License maintenance fee |
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25,000navb_LicenseMaintenanceFee / navb_AgreementsByTypeAxis = navb_TilmanoceptLicenseAgreementMemberDomain
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Minimum annual royalty |
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25,000navb_MinimumAnnualRoyalty / navb_AgreementsByTypeAxis = navb_TilmanoceptLicenseAgreementMemberDomain
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Research and development |
25,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_TilmanoceptLicenseAgreementMemberDomain
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Astra Zeneca Agreement [Member] |
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Agreements [Line Items] |
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Research and development |
81,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember
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5,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember
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14,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember
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Astra Zeneca Agreement [Member] | Milestone Payments Based On Achievement Of Certain Clinical Development And Regulatory Filing Milestones [Member] |
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Agreements [Line Items] |
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License fee |
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5,000,000.0us-gaap_LicenseCosts / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember / navb_AgreementsConditionsAxis = navb_MilestonePaymentsBasedOnAchievementOfCertainClinicalDevelopmentAndRegulatoryFilingMilestonesMember
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Contingent milestone payment |
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6,500,000.0navb_MilestonePaymentsMaximumCash / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember / navb_AgreementsConditionsAxis = navb_MilestonePaymentsBasedOnAchievementOfCertainClinicalDevelopmentAndRegulatoryFilingMilestonesMember
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Astra Zeneca Agreement [Member] | Milestone Payments Based On Receipt Of Certain Regulatory Approvals And Initiation Of Commercial Sales Of Licensed Product [Member] |
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Agreements [Line Items] |
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Contingent milestone payment |
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11,000,000.0navb_MilestonePaymentsMaximumCash / navb_AgreementsByTypeAxis = navb_AstraZenecaAgreementMember / navb_AgreementsConditionsAxis = navb_MilestonePaymentsBasedOnReceiptOfCertainRegulatoryApprovalsAndInitiationOfCommercialSalesOfLicensedProductMember
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Alseres Pharmaceuticals Inc [Member] |
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Agreements [Line Items] |
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Research and development |
42,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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366,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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1,800,000us-gaap_ResearchAndDevelopmentExpense / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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Contingent milestone payment |
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2,900,000.0navb_MilestonePaymentsMaximumCash / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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Sublicense execution payment, cash paid |
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175,000navb_SublicenseExecutionPaymentCashPaid / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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Common Stock, shares issued |
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300,000us-gaap_CommonStockSharesIssued / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember
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Alseres Pharmaceuticals Inc [Member] | Alseres Milestone Payments Based On Product Registration Or Commercial Sales [Member] |
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Agreements [Line Items] |
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Contingent milestone payment |
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2,500,000.0navb_MilestonePaymentsMaximumCash / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember / navb_AgreementsConditionsAxis = navb_AlseresMilestonePaymentsBasedOnProductRegistrationOrCommercialSalesMember
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Common Stock, shares issued |
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950,000us-gaap_CommonStockSharesIssued / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember / navb_AgreementsConditionsAxis = navb_AlseresMilestonePaymentsBasedOnProductRegistrationOrCommercialSalesMember
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Alseres Pharmaceuticals Inc [Member] | Milestone Payments Maximum [Member] |
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Agreements [Line Items] |
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Common Stock, shares issued |
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1,150,000.00us-gaap_CommonStockSharesIssued / navb_AgreementsByTypeAxis = navb_AlseresPharmaceuticalsIncMember / navb_AgreementsConditionsAxis = navb_MilestonePaymentsMaximumMember
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Cardiosonix [Member] |
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Agreements [Line Items] |
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Grants received from Office of the Chief Scientist |
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775,000navb_GrantsReceivedFromOfficeOfChiefScientist / navb_AgreementsByTypeAxis = navb_CardiosonixMember
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Royalty expense |
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84,000us-gaap_RoyaltyExpense / navb_AgreementsByTypeAxis = navb_CardiosonixMember
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Accrued royalties |
0us-gaap_AccruedRoyaltiesCurrentAndNoncurrent / navb_AgreementsByTypeAxis = navb_CardiosonixMember
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0us-gaap_AccruedRoyaltiesCurrentAndNoncurrent / navb_AgreementsByTypeAxis = navb_CardiosonixMember
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Cardiosonix [Member] | Minimum [Member] |
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Agreements [Line Items] |
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Royalty on net sales of licensed products , percentage |
3.00%navb_RoyaltyPercentageFromRevenuesOfLicensedProducts / navb_AgreementsByTypeAxis = navb_CardiosonixMember / us-gaap_RangeAxis = us-gaap_MinimumMember
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Cardiosonix [Member] | Maximum [Member] |
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Agreements [Line Items] |
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Royalty on net sales of licensed products , percentage |
5.00%navb_RoyaltyPercentageFromRevenuesOfLicensedProducts / navb_AgreementsByTypeAxis = navb_CardiosonixMember / us-gaap_RangeAxis = us-gaap_MaximumMember
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Royalty percentage on grant revenues |
300.00%navb_RoyaltyOnGrantRevenue / navb_AgreementsByTypeAxis = navb_CardiosonixMember / us-gaap_RangeAxis = us-gaap_MaximumMember
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Employment Agreement [Member] |
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Agreements [Line Items] |
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Maximum contingent liability |
$ 2,900,000us-gaap_LossContingencyRangeOfPossibleLossMaximum / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember
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$ 2,900,000us-gaap_LossContingencyRangeOfPossibleLossMaximum / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember
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Employment Agreement [Member] | Minimum [Member] |
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Agreements [Line Items] |
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Ratio of entitled salary |
1.2navb_RatioOfEntitledSalary / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember / us-gaap_RangeAxis = us-gaap_MinimumMember
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1.2navb_RatioOfEntitledSalary / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember / us-gaap_RangeAxis = us-gaap_MinimumMember
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Employment Agreement [Member] | Maximum [Member] |
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Agreements [Line Items] |
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Ratio of entitled salary |
2.0navb_RatioOfEntitledSalary / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember / us-gaap_RangeAxis = us-gaap_MaximumMember
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2.0navb_RatioOfEntitledSalary / navb_AgreementsByTypeAxis = navb_EmploymentAgreementMember / us-gaap_RangeAxis = us-gaap_MaximumMember
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