Annual report pursuant to Section 13 and 15(d)

Note 14- Income Taxes (Details Textual)

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Note 14- Income Taxes (Details Textual) - USD ($)
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2018
Jun. 30, 2020
Deferred Tax Assets, Gross, Total $ 48,499,905 $ 45,823,037    
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent 21.00% 21.00%    
Revaluation of Deferred Tax Asset, Decrease     $ (26,400,000)  
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount     $ 26,400,000  
Domestic Tax Authority [Member] | Internal Revenue Service (IRS) [Member]        
Operating Loss Carryforwards, Total $ 164,103,350 $ 153,300,000    
Operating Loss Carryforwards Stock-based Compensation 14,900,000      
State and Local Jurisdiction [Member]        
Operating Loss Carryforwards, Total 20,100,000 20,100,000    
Alternative Minimum Tax [Member]        
Tax Credit Carryforward, Amount       $ 621,000
Research Tax Credit Carryforward [Member] | Domestic Tax Authority [Member] | Internal Revenue Service (IRS) [Member]        
Tax Credit Carryforward, Amount 9,112,411 8,900,000    
Tax Credit Carryforward, Amount Expired During Period $ 0 $ 72,000