Note 14 - Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) |
Dec. 31, 2022 |
Dec. 31, 2021 |
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|---|---|---|---|---|
| Deferred tax assets: | ||||
| Net operating loss carryforwards | $ 39,200,586 | $ 36,793,074 | ||
| R&D credit carryforwards | [1] | 9,256,968 | 9,501,299 | |
| Stock compensation | 286,724 | 481,098 | ||
| Intangibles | 455,959 | 567,213 | ||
| Accrued expenses | 710,940 | 0 | ||
| Capitalized §174 expenses | 1,116,433 | 0 | ||
| Disallowed interest expense | 0 | 851,247 | ||
| Temporary differences | 196,575 | 305,974 | ||
| Deferred tax assets before valuation allowance | 51,224,185 | 48,499,905 | ||
| Valuation allowance | (51,224,185) | (48,499,905) | ||
| Net deferred tax assets | $ 0 | $ 0 | ||
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to capitalized research and development. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to disallowed interest expense. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to research and development tax credit carryforwards. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to temporary differences. No definition available.
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| X | ||||||||||
- Definition Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible interest carryforward. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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| X | ||||||||||
- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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