Consolidated Statements of Operations - USD ($) |
12 Months Ended | ||||||||||
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Dec. 31, 2017 |
Dec. 31, 2016 |
Dec. 31, 2015 |
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| Revenue: | |||||||||||
| Tc99m tilmanocept sales revenue | $ 39,601 | $ 19,075 | |||||||||
| Tc99m tilmanocept license revenue | 100,000 | 1,795,625 | 1,133,333 | ||||||||
| Tc99m tilmanocept royalty revenue | 9,126 | ||||||||||
| Grant and other revenue | 1,701,311 | 3,136,408 | 1,860,953 | ||||||||
| Total revenue | 1,810,437 | 4,971,634 | 3,013,361 | ||||||||
| Cost of goods sold | 3,651 | 62,260 | 3,226 | ||||||||
| Gross profit | 1,806,786 | 4,909,374 | 3,010,135 | ||||||||
| Operating expenses: | |||||||||||
| Research and development | 4,513,842 | 7,138,080 | 10,562,729 | ||||||||
| Selling, general and administrative | 11,169,951 | 7,920,036 | 10,888,146 | ||||||||
| Total operating expenses | 15,683,793 | 15,058,116 | 21,450,875 | ||||||||
| Loss from operations | [1] | (13,877,007) | (10,148,742) | (18,440,740) | |||||||
| Other income (expense): | |||||||||||
| Interest income (expense), net | 168,971 | (4,866) | (1,269,916) | ||||||||
| Equity in loss of R-NAV, LLC | (15,159) | (305,253) | |||||||||
| Loss on disposal of investment in R-NAV, LLC | (39,732) | ||||||||||
| Change in fair value of financial instruments | 153,357 | 2,858,524 | (614,782) | ||||||||
| Loss on extinguishment of debt | (4,201,668) | (2,440,714) | |||||||||
| Other, net | (33,339) | (27,919) | 26,808 | ||||||||
| Total other income (expense), net | (3,912,679) | [2] | 2,770,848 | (4,603,857) | |||||||
| Loss before income taxes | (17,789,686) | (7,377,894) | (23,044,597) | ||||||||
| Benefit from income taxes | 4,062,489 | ||||||||||
| Loss from continuing operations | (13,727,197) | (7,377,894) | (23,044,597) | ||||||||
| Discontinued operations, net of tax effect: | |||||||||||
| Loss from discontinued operations | (490,758) | (6,931,137) | (4,518,938) | [3] | |||||||
| Gain on sale | 89,163,811 | ||||||||||
| Net income (loss) | 74,945,856 | (14,309,031) | (27,563,535) | ||||||||
| Less loss attributable to noncontrolling interest | (210) | (648) | (855) | ||||||||
| Deemed dividend on beneficial conversion feature of MT Preferred Stock | (46,000) | ||||||||||
| Net income (loss) attributable to common stockholders | $ 74,946,066 | $ (14,308,383) | $ (27,608,680) | ||||||||
| Income (loss) per common share (basic): | |||||||||||
| Continuing operations (in dollars per share) | $ (0.08) | $ (0.05) | $ (0.15) | ||||||||
| Discontinued operations (in dollars per share) | 0.55 | (0.04) | (0.03) | ||||||||
| Attributable to common stockholders (in dollars per share) | $ 0.47 | $ (0.09) | $ (0.18) | ||||||||
| Weighted average shares outstanding (basic) (in shares) | 161,592,569 | 155,422,384 | 151,180,222 | ||||||||
| Income (loss) per common share (diluted): | |||||||||||
| Continuing operations (in dollars per share) | $ (0.08) | $ (0.05) | $ (0.15) | ||||||||
| Discontinued operations (in dollars per share) | 0.53 | (0.04) | (0.03) | ||||||||
| Attributable to common stockholders (in dollars per share) | $ 0.45 | $ (0.09) | $ (0.18) | ||||||||
| Weighted average shares outstanding (diluted) (in shares) | 166,016,458 | 155,422,384 | 151,180,222 | ||||||||
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| X | ||||||||||
- Definition The change in fair value of financial instruments recorded during the period. No definition available.
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- References No definition available.
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| X | ||||||||||
- Definition Represents the amount of grant and other revenue recorded during the period. No definition available.
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| X | ||||||||||
- Definition Represents the amount of nonoperating income (expense) recorded during , including equity method investments. No definition available.
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- Definition Total costs related to goods produced and sold during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Amount after tax of gain (loss) not previously recognized resulting from the disposal of a discontinued operation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount after tax of income (loss) from operations classified as a discontinued operation. Excludes gain (loss) on disposal and provision for gain (loss) until disposal. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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| X | ||||||||||
- Definition The amount of net income (loss) for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- References No definition available.
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| X | ||||||||||
- Definition Amount of gain (loss) on sale or disposal of an equity method investment. No definition available.
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| X | ||||||||||
- Definition Difference between the fair value of payments made and the carrying amount of debt which is extinguished prior to maturity. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Aggregate revenue less cost of goods and services sold or operating expenses directly attributable to the revenue generation activity. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount after tax of income (loss) from continuing operations including portion attributable to the noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The amount of net income (loss) from continuing operations per each share of common stock or unit outstanding during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The amount of net income (loss) derived from continuing operations during the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Per basic share amount, after tax, of income (loss) from the day-to-day business activities of the discontinued operation and gain (loss) from the disposal of the discontinued operation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Per diluted share amount, after tax, of income (loss) from the day-to-day business activities of the discontinued operation and gain (loss) from the disposal of the discontinued operation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition This item represents the entity's proportionate share for the period of the net income (loss) of its investee (such as unconsolidated subsidiaries and joint ventures) to which the equity method of accounting is applied. This item includes income or expense related to stock-based compensation based on the investor's grant of stock to employees of an equity method investee. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The net amount of operating interest income (expense). Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount of Net Income (Loss) attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount, after deduction of tax, noncontrolling interests, dividends on preferred stock and participating securities; of income (loss) available to common shareholders. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. No definition available.
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition The net result for the period of deducting operating expenses from operating revenues. No definition available.
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| X | ||||||||||
- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The aggregate value of preferred stock dividends and other adjustments necessary to derive net income apportioned to common stockholders. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The consolidated profit or loss for the period, net of income taxes, including the portion attributable to the noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss). Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Revenue earned during the period from the leasing or otherwise lending to a third party the entity's rights or title to certain property. Royalty revenue is derived from a percentage or stated amount of sales proceeds or revenue generated by the third party using the entity's property. Examples of property from which royalties may be derived include patents and oil and mineral rights. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Aggregate revenue during the period from the sale of goods in the normal course of business, after deducting returns, allowances and discounts. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition The average number of shares or units issued and outstanding that are used in calculating diluted EPS or earnings per unit (EPU), determined based on the timing of issuance of shares or units in the period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Number of [basic] shares or units, after adjustment for contingently issuable shares or units and other shares or units not deemed outstanding, determined by relating the portion of time within a reporting period that common shares or units have been outstanding to the total time in that period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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