Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Stockholders' Equity (Deficit)

Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)	Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	AOCI Attributable to Parent [Member]	Noncontrolling Interest [Member]	Total
Balance (in shares) at Dec. 31, 2014	4,519	150,200,259
Balance at Dec. 31, 2014	$ 4	$ 150,200	$ 323,030,301	$ (352,983,971)	$ 1		$ (29,803,466)
Issued stock upon exercise of stock options, net (in shares)		124,238					146,625
Issued stock upon exercise of stock options, net		$ 124	54,206				$ 54,330
Issued restricted stock (in shares)		354,000
Issued restricted stock		$ 354					354
Canceled forfeited restricted stock (in shares)		(158,000)
Canceled forfeited restricted stock		$ (158)	158
Canceled stock to pay employee tax obligations (in shares)		(7,645)
Canceled stock to pay employee tax obligations		$ (7)	(12,607)				(12,614)
Issued stock in payment of Board retainers (in shares)		90,977
Issued stock in payment of Board retainers		$ 91	172,878				$ 172,969
Issued stock to 401(k) plan (in shares)		68,157					68,157
Issued stock to 401(k) plan		$ 68	117,031				$ 117,099
Exchanged Series B Preferred Stock for warrants (in shares)	(4,519)
Exchanged Series B Preferred Stock for warrants	$ (4)		4
Extension of warrant expiration date			149,615				149,615
Issued warrants in connection with advisory services agreement			256,450				256,450
Issued stock upon exercise of warrants (in shares)		4,977,679
Issued stock upon exercise of warrants		$ 4,978	(4,978)
Stock compensation expense			2,368,685				2,368,685
Net income (loss)				(27,562,680)		(855)	(27,563,535)
Issuance of MT Preferred Stock, net of deemed dividend			(46,000)			470,413	424,413
Balance (in shares) at Dec. 31, 2015		155,649,665
Balance at Dec. 31, 2015		$ 155,650	326,085,743	(380,546,651)		469,558	(53,835,700)
Issued stock in payment of Board retainers (in shares)		90,977
Issued stock upon exercise of warrants		$ 4,978	(4,978)
Unrealized loss on available-for-sale securities
Total comprehensive income							$ (27,563,535)
Issued stock upon exercise of stock options, net (in shares)		50,000					50,000
Issued stock upon exercise of stock options, net		$ 50	13,450				$ 13,500
Issued restricted stock (in shares)		168,000
Issued restricted stock		$ 168					168
Canceled forfeited restricted stock (in shares)		(256,000)
Canceled forfeited restricted stock		$ (256)	228				(28)
Issued stock in payment of Board retainers (in shares)		84,062
Issued stock in payment of Board retainers		$ 84	66,455				$ 66,539
Issued stock to 401(k) plan (in shares)		67,002					67,002
Issued stock to 401(k) plan		$ 67	120,733				$ 120,800
Stock compensation expense			277,539				277,539
Net income (loss)				(14,308,383)		(648)	(14,309,031)
Balance (in shares) at Dec. 31, 2016		155,762,729
Balance at Dec. 31, 2016		$ 155,763	326,564,148	(394,855,034)		468,910	(67,666,213)
Issued stock in payment of Board retainers (in shares)		84,062
Unrealized loss on available-for-sale securities
Total comprehensive income							$ (14,309,031)
Issued stock upon exercise of stock options, net (in shares)		50,000					50,000
Issued stock upon exercise of stock options, net		$ 50	18,050				$ 18,100
Issued restricted stock (in shares)		200,000
Issued restricted stock		$ 200					200
Canceled forfeited restricted stock (in shares)		(50,000)
Canceled forfeited restricted stock		$ (50)	50
Issued stock in payment of Board retainers (in shares)		16,406
Issued stock in payment of Board retainers		$ 17	10,483				$ 10,500
Issued stock to 401(k) plan (in shares)		105,308					105,308
Issued stock to 401(k) plan		$ 105	53,602				$ 53,707
Issued stock upon exercise of warrants		5,412	48,707				54,119
Stock compensation expense			394,209				394,209
Net income (loss)				74,946,066		(210)	74,945,856
Balance (in shares) at Dec. 31, 2017		162,206,646
Balance at Dec. 31, 2017		$ 162,207	331,128,787	(319,908,968)	(2,396)	668,700	12,048,330
Issued stock in payment of Board retainers (in shares)		16,406
Issued stock in payment of employee bonuses (in shares)		710,353
Issued stock in payment of employee bonuses		$ 710	368,632				369,342
Issued stock upon exercise of warrants (in shares)		5,411,850
Issued stock upon exercise of warrants		$ 5,412	48,707				54,119
Issued warrants in connection with Asset Sale			3,337,187				3,337,187
Issued warrants for extension of license agreement			333,719				333,719
Unrealized loss on available-for-sale securities					(2,396)		(2,396)
Total comprehensive income							74,943,460
Reclassification of funds invested (Note 10)						$ 200,000	$ 200,000