Note 20 - Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) |
Dec. 31, 2017 |
Dec. 31, 2016 |
|---|---|---|
| Deferred tax assets: | ||
| Net operating loss carryforwards | $ 29,570,581 | $ 66,150,646 |
| R&D credit carryforwards | 10,043,714 | 9,729,673 |
| AMT credit carryforward | 1,229,979 | |
| Stock compensation | 576,024 | 1,368,458 |
| Intangibles | 591,651 | 1,720,761 |
| Gain/loss from discontinued operations | (2,510,699) | |
| Temporary differences | 207,447 | 132,476 |
| Deferred tax assets before valuation allowance | 39,708,697 | 79,102,014 |
| Valuation allowance | (38,478,718) | (79,102,014) |
| Net deferred tax assets | $ 1,229,979 |
| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to gain/loss form discontinued operations. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to research and development tax credit carryforwards. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to temporary differences. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill. No definition available.
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- References No definition available.
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| X | ||||||||||
- Definition Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible alternative minimum tax credit carryforwards. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from share-based compensation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
- Definition Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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