Annual report pursuant to Section 13 and 15(d)

Note 16 - Commitments and Contingencies (Details Textual)

v3.8.0.1
Note 16 - Commitments and Contingencies (Details Textual) - USD ($)
1 Months Ended 6 Months Ended
Jan. 16, 2018
Nov. 02, 2017
May 16, 2017
May 12, 2017
Mar. 31, 2017
Mar. 03, 2017
Mar. 01, 2017
Oct. 11, 2016
Jun. 22, 2016
Dec. 31, 2017
Jun. 30, 2017
Dec. 31, 2016
Estimated Litigation Liability, Current                   $ 2,887,566  
CRG Loan Agreement, Ohio Case [Member]                        
Release of Cash Held in Escrow           $ 2,000,000            
CRG Loan Agreement, Texas Case [Member]                        
Release of Cash Held in Escrow           3,000,000            
Estimated Litigation Liability, Current                   2,900,000    
CRG Loan Agreement, Texas Case [Member] | Judicial Ruling [Member]                        
Loss Contingency, Damages Awarded, Value, Additional Amount           7,000,000       7,000,000    
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration                   4,100,000    
CRG Loan Agreement, Texas Case [Member] | Judicial Ruling [Member] | Subsequent Event [Member]                        
Loss Contingency, Damages Awarded, Value, Amount not Taken into Consideration $ 4,100,000                      
CRG Loan Agreement, Texas Case [Member] | Pending Litigation [Member] | Subsequent Event [Member]                        
Loss Contingency, Damages Awarded,Value, Requested Modified Amount $ 2,900,000                      
Former CEO Arbitration [Member]                        
Litigation Settlement, Salary, Bonus, and Benefits, Amount Awarded to Other Party       $ 481,039                
Litigation Settlement, Amount Awarded to Other Party     $ 617,880                  
FTI Consulting, Inc. Litigation [Member] | Pending Litigation [Member] | Investigative and Consulting Services [Member]                        
Litigation Settlement, Amount Awarded to Other Party                     $ 435,000  
Loss Contingency, Damages Sought, Value               $ 730,264     $ 862,165  
Platinum-Montaur Life Sciences LLC Litigation [Member] | Pending Litigation [Member]                        
Loss Contingency, Damages Sought, Value   $ 1,914,827.22                    
Minimum [Member] | FTI Consulting, Inc. Litigation [Member] | Pending Litigation [Member]                        
Loss Contingency, Damages Sought, Value               782,600        
Minimum [Member] | FTI Consulting, Inc. Litigation [Member] | Pending Litigation [Member] | Purported Interest Due on Unpaid Invoices, Plus Attorneys' Fees, Costs and Expenses [Member]                        
Loss Contingency, Damages Sought, Value               $ 52,337        
Maximum [Member] | CRG Loan Agreement, Texas Case [Member] | Judicial Ruling [Member]                        
Loss Contingency, Damages Awarded, Value           66,000,000       $ 66,000,000    
Term Loan Agreement [Member] | Cardinal Health 414 [Member]                        
Letters of Credit Outstanding, Amount           7,000,000            
Term Loan Agreement [Member] | CRG [Member]                        
Letters of Credit Outstanding, Amount           12,000,000            
CRG [Member] | Term Loan Agreement [Member]                        
Primary Bank Account Cash Taken Possession Of By Creditor                 $ 4,100,000      
Primary Bank Account Cash Taken Possession Of By Creditor, Portion Applied to Fees                 3,900,000      
Primary Bank Account Cash Taken Possession Of By Creditor, Portion Applied to the Principal Balance of Debt                 $ 189,000      
Repayments of Debt           59,000,000            
Debt Instrument, Final Payoff Amount, Threshold Above Which the Reporting Entity Will First Pay Without Resorting to Letter of Credit           59,000,000            
CRG [Member] | Term Loan Agreement [Member] | CRG Loan Agreement, Texas Case [Member] | Judicial Ruling [Member]                        
Repayments of Debt         $ 59,000,000 59,000,000 $ 59,000,000          
CRG [Member] | Term Loan Agreement [Member] | Minimum [Member]                        
Debt Instrument, Agreed-upon Final Payoff Amount           47,000,000            
CRG [Member] | Term Loan Agreement [Member] | Maximum [Member]                        
Debt Instrument, Agreed-upon Final Payoff Amount           $ 66,000,000